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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDYL2
All Species:
17.27
Human Site:
S121
Identified Species:
34.55
UniProt:
Q8N8U2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8U2
NP_689555.2
506
56500
S121
A
K
P
K
K
G
Y
S
G
K
P
S
S
G
G
Chimpanzee
Pan troglodytes
XP_523432
546
60834
S161
A
X
P
K
K
G
Y
S
G
K
P
S
S
G
G
Rhesus Macaque
Macaca mulatta
XP_001108466
603
66957
S218
A
K
P
K
K
G
Y
S
G
K
P
P
A
G
G
Dog
Lupus familis
XP_546818
522
57899
S138
S
K
P
K
K
G
Y
S
G
K
P
P
A
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK2
593
65193
K170
A
A
S
Q
K
F
R
K
N
P
A
P
S
L
A
Rat
Rattus norvegicus
Q6AYK9
589
65012
N170
T
S
Q
K
F
R
K
N
T
A
P
S
L
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507630
676
75369
K253
T
A
S
Q
K
L
R
K
N
T
S
P
S
L
S
Chicken
Gallus gallus
XP_423582
547
60918
T161
Q
K
Q
K
R
G
Y
T
A
K
P
A
S
A
N
Frog
Xenopus laevis
NP_001089808
358
40132
N14
D
F
E
K
A
Q
S
N
L
K
L
L
K
N
D
Zebra Danio
Brachydanio rerio
XP_696879
437
47423
M93
P
G
E
E
R
A
R
M
G
T
R
P
R
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392910
1069
119281
S390
I
R
I
D
E
S
R
S
G
R
K
R
K
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781347
617
67230
I222
R
V
K
R
A
H
S
I
T
G
V
G
P
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
82.2
92.9
N.A.
47
46.6
N.A.
40
79.1
25.6
44.6
N.A.
N.A.
20.3
N.A.
34.3
Protein Similarity:
100
91.9
83.2
94.6
N.A.
60
59.7
N.A.
54.2
85.1
42.4
59.2
N.A.
N.A.
30.7
N.A.
51.2
P-Site Identity:
100
93.3
86.6
80
N.A.
20
20
N.A.
13.3
46.6
13.3
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
26.6
26.6
N.A.
20
66.6
20
20
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
17
0
0
17
9
0
0
9
9
9
9
17
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
17
9
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
42
0
0
50
9
0
9
0
34
42
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
34
9
59
50
0
9
17
0
50
9
0
17
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
9
0
9
9
9
25
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
17
0
0
0
0
9
17
% N
% Pro:
9
0
34
0
0
0
0
0
0
9
50
42
9
0
0
% P
% Gln:
9
0
17
17
0
9
0
0
0
0
0
0
0
9
9
% Q
% Arg:
9
9
0
9
17
9
34
0
0
9
9
9
9
0
0
% R
% Ser:
9
9
17
0
0
9
17
42
0
0
9
25
42
0
9
% S
% Thr:
17
0
0
0
0
0
0
9
17
17
0
0
0
9
9
% T
% Val:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _