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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDYL2
All Species:
30.91
Human Site:
S270
Identified Species:
61.82
UniProt:
Q8N8U2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8U2
NP_689555.2
506
56500
S270
I
L
L
S
S
Q
T
S
D
N
N
A
L
T
P
Chimpanzee
Pan troglodytes
XP_523432
546
60834
S310
I
L
L
S
S
Q
T
S
D
N
N
A
L
T
P
Rhesus Macaque
Macaca mulatta
XP_001108466
603
66957
S367
I
L
L
S
S
Q
T
S
D
N
N
A
L
T
P
Dog
Lupus familis
XP_546818
522
57899
S286
I
L
L
S
S
Q
T
S
D
N
N
A
L
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK2
593
65193
S357
I
L
L
S
T
K
S
S
E
N
N
S
L
N
P
Rat
Rattus norvegicus
Q6AYK9
589
65012
S353
I
L
L
S
T
K
S
S
E
N
N
S
L
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507630
676
75369
S440
I
L
L
S
T
K
S
S
E
N
N
S
L
N
P
Chicken
Gallus gallus
XP_423582
547
60918
S311
I
L
L
S
S
Q
T
S
D
N
N
A
L
T
P
Frog
Xenopus laevis
NP_001089808
358
40132
V152
K
D
E
S
V
F
A
V
L
S
G
V
G
D
Y
Zebra Danio
Brachydanio rerio
XP_696879
437
47423
L231
D
D
S
K
L
V
L
L
S
G
V
G
S
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392910
1069
119281
K834
L
T
P
S
S
S
T
K
I
R
N
A
L
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781347
617
67230
P382
V
R
L
F
T
T
T
P
T
R
N
A
L
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
82.2
92.9
N.A.
47
46.6
N.A.
40
79.1
25.6
44.6
N.A.
N.A.
20.3
N.A.
34.3
Protein Similarity:
100
91.9
83.2
94.6
N.A.
60
59.7
N.A.
54.2
85.1
42.4
59.2
N.A.
N.A.
30.7
N.A.
51.2
P-Site Identity:
100
100
100
100
N.A.
60
60
N.A.
60
100
6.6
0
N.A.
N.A.
46.6
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
100
13.3
0
N.A.
N.A.
53.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
59
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
0
0
0
0
0
42
0
0
0
0
9
0
% D
% Glu:
0
0
9
0
0
0
0
0
25
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
9
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
9
0
0
9
0
25
0
9
0
0
0
0
0
0
0
% K
% Leu:
9
67
75
0
9
0
9
9
9
0
0
0
84
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
67
84
0
0
34
0
% N
% Pro:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
67
% P
% Gln:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
17
0
0
0
0
0
% R
% Ser:
0
0
9
84
50
9
25
67
9
9
0
25
9
0
0
% S
% Thr:
0
9
0
0
34
9
59
0
9
0
0
0
0
50
0
% T
% Val:
9
0
0
0
9
9
0
9
0
0
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _