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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKS4B
All Species:
19.39
Human Site:
S290
Identified Species:
38.79
UniProt:
Q8N8V4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8V4
NP_665872.2
460
51187
S290
S
P
E
D
I
S
D
S
K
R
E
F
G
F
K
Chimpanzee
Pan troglodytes
XP_001159529
417
46659
S290
S
P
E
D
I
S
D
S
K
R
E
L
G
F
K
Rhesus Macaque
Macaca mulatta
XP_001091739
417
46809
S290
S
P
E
D
I
S
D
S
K
R
E
L
G
F
K
Dog
Lupus familis
XP_547100
417
46709
I290
S
P
E
D
M
S
D
I
K
R
G
L
E
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3X6
423
47957
S289
D
F
E
D
I
S
D
S
K
R
E
L
G
F
K
Rat
Rattus norvegicus
NP_001121122
416
46812
S289
D
L
E
E
I
S
A
S
K
R
E
L
E
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508254
420
47192
D294
G
I
N
S
A
Q
E
D
I
S
T
S
T
R
D
Chicken
Gallus gallus
XP_424609
403
44955
S281
D
I
D
P
G
T
V
S
S
Q
K
E
G
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002188
422
46925
D300
E
M
A
M
D
P
E
D
L
P
I
G
N
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610829
516
56491
L354
E
L
S
E
E
V
T
L
Q
R
P
V
G
L
F
Honey Bee
Apis mellifera
XP_001120815
521
58324
S386
T
F
D
N
L
P
L
S
Q
M
D
A
H
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783343
422
46145
D290
T
L
D
N
S
I
D
D
A
T
G
D
P
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.1
86.7
79.1
N.A.
75.6
74.3
N.A.
61.2
49.1
N.A.
43.2
N.A.
25.9
25.7
N.A.
25
Protein Similarity:
100
89.5
87.3
83.2
N.A.
80.8
79.7
N.A.
73.6
64.7
N.A.
59.3
N.A.
40.5
41.8
N.A.
44.1
P-Site Identity:
100
93.3
93.3
66.6
N.A.
80
60
N.A.
0
13.3
N.A.
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
80
66.6
N.A.
6.6
40
N.A.
13.3
N.A.
26.6
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
9
0
9
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
25
42
9
0
50
25
0
0
9
9
0
0
9
% D
% Glu:
17
0
50
17
9
0
17
0
0
0
42
9
17
9
17
% E
% Phe:
0
17
0
0
0
0
0
0
0
0
0
9
0
50
9
% F
% Gly:
9
0
0
0
9
0
0
0
0
0
17
9
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
17
0
0
42
9
0
9
9
0
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
50
0
9
0
0
0
50
% K
% Leu:
0
25
0
0
9
0
9
9
9
0
0
42
0
9
0
% L
% Met:
0
9
0
9
9
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
17
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
34
0
9
0
17
0
0
0
9
9
0
9
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
17
9
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
59
0
0
0
9
0
% R
% Ser:
34
0
9
9
9
50
0
59
9
9
0
9
0
9
9
% S
% Thr:
17
0
0
0
0
9
9
0
0
9
9
0
9
9
0
% T
% Val:
0
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _