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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA1
All Species:
9.09
Human Site:
S323
Identified Species:
18.18
UniProt:
Q8N8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8W4
NP_001139188.1
532
57875
S323
P
K
G
D
G
R
G
S
H
G
P
P
V
S
Q
Chimpanzee
Pan troglodytes
XP_001172868
533
57936
S324
P
K
G
D
G
R
G
S
H
G
P
P
V
S
Q
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
S282
A
P
G
W
E
N
T
S
L
D
S
S
P
E
P
Dog
Lupus familis
XP_538884
607
65658
S324
E
G
K
G
S
H
G
S
L
P
S
S
P
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1D5
599
65152
S323
P
K
K
D
R
K
D
S
H
S
S
A
A
P
S
Rat
Rattus norvegicus
P0C548
478
52548
V279
E
D
A
E
E
A
A
V
T
E
E
R
T
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
T191
V
S
P
F
F
G
E
T
D
I
C
P
K
T
Q
Chicken
Gallus gallus
XP_425818
376
41593
L177
V
D
G
G
F
T
G
L
Q
P
V
S
S
L
E
Frog
Xenopus laevis
NP_001087449
506
56166
W306
V
L
E
G
Q
T
P
W
S
L
D
K
R
I
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
L307
I
E
Q
A
N
K
G
L
A
N
W
I
F
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
I333
I
P
L
E
E
V
N
I
Q
S
F
F
P
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T076
349
35046
P150
A
A
P
G
S
S
T
P
G
S
M
T
P
P
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.6
66.8
N.A.
56.4
29.5
N.A.
28.2
35.9
31.2
N.A.
N.A.
25.5
N.A.
25.1
N.A.
Protein Similarity:
100
98.8
42.6
72.8
N.A.
65.6
45.4
N.A.
42.8
50.9
48.6
N.A.
N.A.
43.7
N.A.
41.7
N.A.
P-Site Identity:
100
100
13.3
20
N.A.
33.3
0
N.A.
13.3
13.3
0
N.A.
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
40
6.6
N.A.
26.6
20
0
N.A.
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
9
0
9
9
0
9
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
17
0
25
0
0
9
0
9
9
9
0
0
0
0
% D
% Glu:
17
9
9
17
25
0
9
0
0
9
9
0
0
9
9
% E
% Phe:
0
0
0
9
17
0
0
0
0
0
9
9
9
0
0
% F
% Gly:
0
9
34
34
17
9
42
0
9
17
0
0
0
9
17
% G
% His:
0
0
0
0
0
9
0
0
25
0
0
0
0
0
9
% H
% Ile:
17
0
0
0
0
0
0
9
0
9
0
9
0
9
9
% I
% Lys:
0
25
17
0
0
17
0
0
0
0
0
9
9
9
0
% K
% Leu:
0
9
9
0
0
0
0
17
17
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% M
% Asn:
0
0
0
0
9
9
9
0
0
9
0
0
0
0
0
% N
% Pro:
25
17
17
0
0
0
9
9
0
17
17
25
34
17
9
% P
% Gln:
0
0
9
0
9
0
0
0
17
0
0
0
0
0
34
% Q
% Arg:
0
0
0
0
9
17
0
0
0
0
0
9
9
0
0
% R
% Ser:
0
9
0
0
17
9
0
42
9
25
25
25
9
25
9
% S
% Thr:
0
0
0
0
0
17
17
9
9
0
0
9
9
9
0
% T
% Val:
25
0
0
0
0
9
0
9
0
0
9
0
17
9
0
% V
% Trp:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _