KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA1
All Species:
5.45
Human Site:
S348
Identified Species:
10.91
UniProt:
Q8N8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8W4
NP_001139188.1
532
57875
S348
S
P
V
S
A
P
V
S
P
L
E
Q
P
P
A
Chimpanzee
Pan troglodytes
XP_001172868
533
57936
S349
S
P
V
S
A
P
V
S
P
L
E
Q
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
L307
E
L
L
D
H
L
R
L
S
I
L
P
W
D
E
Dog
Lupus familis
XP_538884
607
65658
V349
E
S
P
V
S
P
P
V
P
S
L
E
Q
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1D5
599
65152
L348
S
V
E
S
P
V
S
L
R
V
S
I
S
K
Q
Rat
Rattus norvegicus
P0C548
478
52548
E304
R
L
N
E
A
L
L
E
A
C
V
E
P
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
L216
H
L
N
Y
H
V
S
L
G
N
A
Y
L
T
S
Chicken
Gallus gallus
XP_425818
376
41593
R202
G
E
L
D
I
C
P
R
D
C
P
A
I
F
Y
Frog
Xenopus laevis
NP_001087449
506
56166
K331
L
Q
E
A
C
R
E
K
N
G
L
Y
H
Q
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
L332
T
V
P
M
D
F
L
L
A
T
I
S
K
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
Y358
A
E
R
S
V
F
Q
Y
M
M
S
F
R
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T076
349
35046
P175
V
S
P
T
T
S
P
P
G
S
T
T
P
P
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.6
66.8
N.A.
56.4
29.5
N.A.
28.2
35.9
31.2
N.A.
N.A.
25.5
N.A.
25.1
N.A.
Protein Similarity:
100
98.8
42.6
72.8
N.A.
65.6
45.4
N.A.
42.8
50.9
48.6
N.A.
N.A.
43.7
N.A.
41.7
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
13.3
13.3
N.A.
0
0
0
N.A.
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
26.6
N.A.
20
26.6
N.A.
6.6
6.6
6.6
N.A.
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
25
0
0
0
17
0
9
9
0
0
17
% A
% Cys:
0
0
0
0
9
9
0
0
0
17
0
0
0
0
0
% C
% Asp:
0
0
0
17
9
0
0
0
9
0
0
0
0
9
9
% D
% Glu:
17
17
17
9
0
0
9
9
0
0
17
17
0
0
9
% E
% Phe:
0
0
0
0
0
17
0
0
0
0
0
9
0
9
0
% F
% Gly:
9
0
0
0
0
0
0
0
17
9
0
0
0
0
9
% G
% His:
9
0
0
0
17
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
9
9
9
9
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
9
17
0
% K
% Leu:
9
25
17
0
0
17
17
34
0
17
25
0
9
9
0
% L
% Met:
0
0
0
9
0
0
0
0
9
9
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
17
25
0
9
25
25
9
25
0
9
9
34
25
9
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
0
17
9
9
9
% Q
% Arg:
9
0
9
0
0
9
9
9
9
0
0
0
9
0
0
% R
% Ser:
25
17
0
34
9
9
17
17
9
17
17
9
9
9
17
% S
% Thr:
9
0
0
9
9
0
0
0
0
9
9
9
0
9
0
% T
% Val:
9
17
17
9
9
17
17
9
0
9
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
9
0
0
0
9
0
0
0
17
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _