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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA1
All Species:
6.67
Human Site:
S397
Identified Species:
13.33
UniProt:
Q8N8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8W4
NP_001139188.1
532
57875
S397
P
T
P
P
P
G
L
S
P
L
S
P
Q
Q
Q
Chimpanzee
Pan troglodytes
XP_001172868
533
57936
S398
P
T
P
P
P
G
L
S
P
L
S
P
Q
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
L356
R
I
M
S
Y
V
M
L
P
C
T
L
P
V
E
Dog
Lupus familis
XP_538884
607
65658
V398
R
V
S
P
Q
Q
Q
V
Q
T
T
G
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1D5
599
65152
D397
R
G
V
K
G
A
L
D
S
A
T
E
R
G
M
Rat
Rattus norvegicus
P0C548
478
52548
V353
L
L
E
W
L
P
D
V
P
E
D
I
R
W
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
P265
P
A
P
D
R
G
L
P
P
L
P
S
S
E
L
Chicken
Gallus gallus
XP_425818
376
41593
T251
F
F
Q
G
Y
Q
D
T
A
L
F
L
C
R
N
Frog
Xenopus laevis
NP_001087449
506
56166
R380
P
D
M
P
E
D
M
R
W
M
Q
E
Q
V
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
D381
L
Y
D
Q
P
H
F
D
A
T
G
L
L
H
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
R407
R
W
I
M
L
K
F
R
G
L
A
D
F
I
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T076
349
35046
T224
P
P
A
P
P
K
S
T
S
P
V
S
P
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.6
66.8
N.A.
56.4
29.5
N.A.
28.2
35.9
31.2
N.A.
N.A.
25.5
N.A.
25.1
N.A.
Protein Similarity:
100
98.8
42.6
72.8
N.A.
65.6
45.4
N.A.
42.8
50.9
48.6
N.A.
N.A.
43.7
N.A.
41.7
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
6.6
N.A.
40
6.6
20
N.A.
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
13.3
N.A.
20
13.3
N.A.
46.6
20
33.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
9
0
0
17
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
9
% C
% Asp:
0
9
9
9
0
9
17
17
0
0
9
9
0
0
0
% D
% Glu:
0
0
9
0
9
0
0
0
0
9
0
17
0
9
9
% E
% Phe:
9
9
0
0
0
0
17
0
0
0
9
0
9
0
0
% F
% Gly:
0
9
0
9
9
25
0
0
9
0
9
9
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
9
0
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
9
0
0
17
0
34
9
0
42
0
25
9
0
17
% L
% Met:
0
0
17
9
0
0
17
0
0
9
0
0
0
0
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
42
9
25
42
34
9
0
9
42
9
9
17
17
9
9
% P
% Gln:
0
0
9
9
9
17
9
0
9
0
9
0
25
17
17
% Q
% Arg:
34
0
0
0
9
0
0
17
0
0
0
0
17
9
0
% R
% Ser:
0
0
9
9
0
0
9
17
17
0
17
17
17
9
17
% S
% Thr:
0
17
0
0
0
0
0
17
0
17
25
0
0
0
0
% T
% Val:
0
9
9
0
0
9
0
17
0
0
9
0
0
17
0
% V
% Trp:
0
9
0
9
0
0
0
0
9
0
0
0
0
9
0
% W
% Tyr:
0
9
0
0
17
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _