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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA1
All Species:
6.67
Human Site:
S410
Identified Species:
13.33
UniProt:
Q8N8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8W4
NP_001139188.1
532
57875
S410
Q
Q
V
Q
P
S
G
S
P
A
R
S
L
H
S
Chimpanzee
Pan troglodytes
XP_001172868
533
57936
S411
Q
Q
V
Q
P
S
G
S
P
A
R
S
P
H
S
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
V369
V
E
S
A
I
A
I
V
Q
R
L
V
T
W
L
Dog
Lupus familis
XP_538884
607
65658
Q411
P
P
R
S
P
P
S
Q
S
S
L
S
H
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1D5
599
65152
S410
G
M
K
D
A
L
A
S
A
T
D
E
Q
S
T
Rat
Rattus norvegicus
P0C548
478
52548
S366
W
M
K
E
Q
T
G
S
I
C
Q
Y
L
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
G278
E
L
P
A
V
E
R
G
L
G
G
H
L
K
P
Chicken
Gallus gallus
XP_425818
376
41593
N264
R
N
N
A
F
G
V
N
Y
F
D
G
N
F
R
Frog
Xenopus laevis
NP_001087449
506
56166
V393
V
C
S
V
A
G
A
V
Y
S
Q
A
K
K
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
P394
H
S
S
R
L
Y
G
P
R
V
S
I
L
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
Q420
I
L
G
E
V
E
K
Q
K
S
R
Y
T
N
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T076
349
35046
P237
S
S
A
P
M
T
S
P
P
A
P
M
A
P
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.6
66.8
N.A.
56.4
29.5
N.A.
28.2
35.9
31.2
N.A.
N.A.
25.5
N.A.
25.1
N.A.
Protein Similarity:
100
98.8
42.6
72.8
N.A.
65.6
45.4
N.A.
42.8
50.9
48.6
N.A.
N.A.
43.7
N.A.
41.7
N.A.
P-Site Identity:
100
93.3
0
13.3
N.A.
6.6
20
N.A.
6.6
0
0
N.A.
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
13.3
20
N.A.
13.3
40
N.A.
13.3
13.3
20
N.A.
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
25
17
9
17
0
9
25
0
9
9
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
17
0
0
0
9
% D
% Glu:
9
9
0
17
0
17
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
9
% F
% Gly:
9
0
9
0
0
17
34
9
0
9
9
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
9
17
0
% H
% Ile:
9
0
0
0
9
0
9
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
17
0
0
0
9
0
9
0
0
0
9
17
9
% K
% Leu:
0
17
0
0
9
9
0
0
9
0
17
0
34
0
9
% L
% Met:
0
17
0
0
9
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
9
9
0
0
0
0
9
0
0
0
0
9
9
0
% N
% Pro:
9
9
9
9
25
9
0
17
25
0
9
0
9
9
17
% P
% Gln:
17
17
0
17
9
0
0
17
9
0
17
0
9
0
0
% Q
% Arg:
9
0
9
9
0
0
9
0
9
9
25
0
0
9
17
% R
% Ser:
9
17
25
9
0
17
17
34
9
25
9
25
0
9
17
% S
% Thr:
0
0
0
0
0
17
0
0
0
9
0
0
17
0
9
% T
% Val:
17
0
17
9
17
0
9
17
0
9
0
9
0
17
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
9
0
0
17
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _