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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA1
All Species:
4.24
Human Site:
Y488
Identified Species:
8.48
UniProt:
Q8N8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8W4
NP_001139188.1
532
57875
Y488
K
E
T
V
S
K
P
Y
V
T
E
S
P
A
E
Chimpanzee
Pan troglodytes
XP_001172868
533
57936
Y489
K
E
T
V
S
K
P
Y
V
M
E
S
P
A
E
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
A438
C
S
P
E
D
C
P
A
E
A
K
A
E
A
T
Dog
Lupus familis
XP_538884
607
65658
W490
N
P
T
E
D
S
S
W
M
S
K
V
F
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1D5
599
65152
P515
G
K
K
A
P
H
K
P
L
L
V
E
G
P
G
Rat
Rattus norvegicus
P0C548
478
52548
R435
A
K
W
E
E
C
Q
R
Q
L
L
L
G
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
A347
V
R
V
L
S
L
V
A
L
P
C
T
L
P
V
Chicken
Gallus gallus
XP_425818
376
41593
P333
L
L
Q
P
Y
K
L
P
A
F
V
W
K
G
L
Frog
Xenopus laevis
NP_001087449
506
56166
P463
D
H
Q
D
P
S
S
P
P
T
E
L
D
S
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
V483
H
Q
H
S
H
N
T
V
V
S
E
W
N
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
D503
E
T
S
V
Y
D
V
D
S
F
E
H
V
I
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T076
349
35046
G306
A
M
G
P
S
G
D
G
P
S
A
A
G
D
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.6
66.8
N.A.
56.4
29.5
N.A.
28.2
35.9
31.2
N.A.
N.A.
25.5
N.A.
25.1
N.A.
Protein Similarity:
100
98.8
42.6
72.8
N.A.
65.6
45.4
N.A.
42.8
50.9
48.6
N.A.
N.A.
43.7
N.A.
41.7
N.A.
P-Site Identity:
100
93.3
13.3
6.6
N.A.
0
0
N.A.
6.6
6.6
13.3
N.A.
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
26.6
40
N.A.
13.3
6.6
N.A.
26.6
6.6
20
N.A.
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
0
0
17
9
9
9
17
0
25
0
% A
% Cys:
9
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
9
17
9
9
9
0
0
0
0
9
9
9
% D
% Glu:
9
17
0
25
9
0
0
0
9
0
42
9
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
9
% F
% Gly:
9
0
9
0
0
9
0
9
0
0
0
0
25
17
9
% G
% His:
9
9
9
0
9
9
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
17
17
9
0
0
25
9
0
0
0
17
0
9
9
9
% K
% Leu:
9
9
0
9
0
9
9
0
17
17
9
17
9
9
9
% L
% Met:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
9
9
17
17
0
25
25
17
9
0
0
17
17
0
% P
% Gln:
0
9
17
0
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
9
34
17
17
0
9
25
0
17
0
9
0
% S
% Thr:
0
9
25
0
0
0
9
0
0
17
0
9
0
0
9
% T
% Val:
9
0
9
25
0
0
17
9
25
0
17
9
9
0
25
% V
% Trp:
0
0
9
0
0
0
0
9
0
0
0
17
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _