KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0D2
All Species:
35.15
Human Site:
T146
Identified Species:
51.56
UniProt:
Q8N8Y2
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Y2
NP_689778.1
350
40426
T146
E
A
V
N
I
A
E
T
P
S
D
L
F
N
A
Chimpanzee
Pan troglodytes
XP_001163802
351
40445
T146
E
A
V
N
I
A
Q
T
P
A
E
L
Y
N
A
Rhesus Macaque
Macaca mulatta
XP_001082286
350
40384
T146
E
A
V
N
I
A
E
T
P
S
D
L
F
N
A
Dog
Lupus familis
XP_535118
351
40722
T146
E
A
V
N
I
A
E
T
P
S
D
L
F
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80SY3
350
40475
T146
E
A
V
N
I
A
E
T
P
S
D
L
F
K
A
Rat
Rattus norvegicus
Q5FVL0
350
40501
S146
E
A
V
N
I
A
E
S
A
S
E
L
F
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHL0
351
40381
N146
E
A
V
S
I
A
S
N
P
T
E
L
F
N
A
Frog
Xenopus laevis
NP_001080200
351
40190
T146
E
A
V
N
I
A
Q
T
P
A
E
L
Y
N
A
Zebra Danio
Brachydanio rerio
NP_955914
350
40172
T145
E
A
V
N
I
A
Q
T
P
A
E
L
Y
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4P5
350
39833
T145
E
A
I
H
V
A
S
T
P
A
E
L
Y
N
A
Honey Bee
Apis mellifera
XP_393438
348
39548
P144
A
I
H
V
A
A
T
P
A
E
L
Y
N
A
V
Nematode Worm
Caenorhab. elegans
NP_491515
348
39919
P144
A
I
H
I
A
S
T
P
A
E
L
Y
N
A
V
Sea Urchin
Strong. purpuratus
XP_779935
348
39778
P144
A
V
N
V
A
Q
T
P
A
D
L
Y
N
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI5
351
40773
N146
A
T
L
A
V
A
Q
N
M
R
E
L
Y
R
L
Baker's Yeast
Sacchar. cerevisiae
P32366
345
39772
D144
P
T
L
S
V
A
T
D
L
E
S
L
Y
E
T
Red Bread Mold
Neurospora crassa
P53659
364
40989
V150
I
E
E
L
Y
N
S
V
M
I
E
T
P
L
A
Conservation
Percent
Protein Identity:
100
65.8
98.8
94.8
N.A.
93.1
92
N.A.
N.A.
70.9
66.3
66.8
N.A.
62
62
61.7
62.5
Protein Similarity:
100
81.4
99.4
97.4
N.A.
97.4
96.5
N.A.
N.A.
84.6
82.6
83.1
N.A.
80.8
80.5
80.2
81.1
P-Site Identity:
100
73.3
100
100
N.A.
93.3
73.3
N.A.
N.A.
66.6
73.3
73.3
N.A.
53.3
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
86.6
100
100
N.A.
93.3
6.6
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
44
48.9
Protein Similarity:
N.A.
N.A.
N.A.
67.8
64
68.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
63
0
7
19
82
0
0
25
25
0
0
0
19
69
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
7
25
0
0
0
0
% D
% Glu:
63
7
7
0
0
0
32
0
0
19
50
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
13
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
13
7
7
57
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% K
% Leu:
0
0
13
7
0
0
0
0
7
0
19
75
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
0
7
50
0
7
0
13
0
0
0
0
19
50
0
% N
% Pro:
7
0
0
0
0
0
0
19
57
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
7
25
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% R
% Ser:
0
0
0
13
0
7
19
7
0
32
7
0
0
0
0
% S
% Thr:
0
13
0
0
0
0
25
50
0
7
0
7
0
0
7
% T
% Val:
0
7
57
13
19
0
0
7
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
19
38
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _