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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM123C All Species: 10
Human Site: S191 Identified Species: 44
UniProt: Q8N944 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N944 NP_001098663.1 861 90455 S191 L P S P G D P S D P G G R R S
Chimpanzee Pan troglodytes XP_001144402 861 90276 S191 L P S P G D P S D P G G R R S
Rhesus Macaque Macaca mulatta XP_001094495 861 90278 S191 L P S P G D P S D P G G R Q S
Dog Lupus familis XP_848346 1130 123421 A202 K G P E G A R A R P H E Y V S
Cat Felis silvestris
Mouse Mus musculus Q6NS69 780 83141 K145 V A K S I P R K R I S L K R S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232634 841 91023 S185 K R I S L K R S K K G L R D I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 93.1 21.2 N.A. 60.5 N.A. N.A. N.A. 36.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 95.4 34.3 N.A. 68.5 N.A. N.A. N.A. 50 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 20 N.A. 13.3 N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 26.6 N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 17 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 50 0 0 50 0 0 0 0 17 0 % D
% Glu: 0 0 0 17 0 0 0 0 0 0 0 17 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 0 0 67 0 0 0 0 0 67 50 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % H
% Ile: 0 0 17 0 17 0 0 0 0 17 0 0 0 0 17 % I
% Lys: 34 0 17 0 0 17 0 17 17 17 0 0 17 0 0 % K
% Leu: 50 0 0 0 17 0 0 0 0 0 0 34 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 50 17 50 0 17 50 0 0 67 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % Q
% Arg: 0 17 0 0 0 0 50 0 34 0 0 0 67 50 0 % R
% Ser: 0 0 50 34 0 0 0 67 0 0 17 0 0 0 84 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 17 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _