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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC22 All Species: 24.24
Human Site: S255 Identified Species: 59.26
UniProt: Q8N966 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N966 NP_777636.2 263 29100 S255 V P M F N V G S E S S K Q Q D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094840 263 29109 S255 V P M F N V G S E S S K Q Q D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A0PK84 263 29299 T255 V P M F N V G T E S S K Q Q D
Rat Rattus norvegicus Q2TGI8 263 29230 T255 V P M F N V G T E S S K Q Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505597 271 29672 S263 I P V L N V G S E Y H Q Q K D
Chicken Gallus gallus XP_426450 275 30622 S267 I P M L N V G S D C R R Q K V
Frog Xenopus laevis Q5FWL7 338 39422 S323 D D L T D E E S Q A Y C E T S
Zebra Danio Brachydanio rerio XP_001340992 276 31149 T262 V P V P T V E T V P G N W Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190341 283 32925 R273 D G I H F V K R D K S L E N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RWM9 429 49597 A326 V Y K R R M A A D G S R E K D
Conservation
Percent
Protein Identity: 100 N.A. 99.2 N.A. N.A. 92.4 92.7 N.A. 80.4 76.3 20.4 47 N.A. N.A. N.A. N.A. 28.2
Protein Similarity: 100 N.A. 99.2 N.A. N.A. 96.5 96.9 N.A. 86.3 86.9 33.4 63 N.A. N.A. N.A. N.A. 45.9
P-Site Identity: 100 N.A. 100 N.A. N.A. 93.3 93.3 N.A. 53.3 46.6 6.6 26.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 80 73.3 40 40 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 34.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % C
% Asp: 20 10 0 0 10 0 0 0 30 0 0 0 0 0 60 % D
% Glu: 0 0 0 0 0 10 20 0 50 0 0 0 30 0 0 % E
% Phe: 0 0 0 40 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 60 0 0 10 10 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 20 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 10 0 40 0 30 0 % K
% Leu: 0 0 10 20 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 50 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 60 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 0 70 0 10 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 10 60 50 0 % Q
% Arg: 0 0 0 10 10 0 0 10 0 0 10 20 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 40 60 0 0 0 10 % S
% Thr: 0 0 0 10 10 0 0 30 0 0 0 0 0 10 0 % T
% Val: 60 0 20 0 0 80 0 0 10 0 0 0 0 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _