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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC22 All Species: 3.94
Human Site: S91 Identified Species: 9.63
UniProt: Q8N966 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N966 NP_777636.2 263 29100 S91 A R K T P C P S P S T H F C R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094840 263 29109 S91 T R K V P C P S P S T H F C R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A0PK84 263 29299 P91 S Q R P Q C P P P S T H F C R
Rat Rattus norvegicus Q2TGI8 263 29230 P91 S Q R P Q R P P P S T H F C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505597 271 29672 K99 G R A E G A R K P G A H F C R
Chicken Gallus gallus XP_426450 275 30622 L103 S R S P G S A L P S T H Y C R
Frog Xenopus laevis Q5FWL7 338 39422 F177 N Y K F F L L F L A Y A M L Y
Zebra Danio Brachydanio rerio XP_001340992 276 31149 L97 R I D A H Y L L N G R H F C K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190341 283 32925 P102 P S C T L N T P P R S S H C F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RWM9 429 49597 P166 E T C H L L K P A R S K H C S
Conservation
Percent
Protein Identity: 100 N.A. 99.2 N.A. N.A. 92.4 92.7 N.A. 80.4 76.3 20.4 47 N.A. N.A. N.A. N.A. 28.2
Protein Similarity: 100 N.A. 99.2 N.A. N.A. 96.5 96.9 N.A. 86.3 86.9 33.4 63 N.A. N.A. N.A. N.A. 45.9
P-Site Identity: 100 N.A. 86.6 N.A. N.A. 60 53.3 N.A. 40 46.6 6.6 20 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 N.A. 86.6 N.A. N.A. 80 73.3 N.A. 40 60 13.3 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 34.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 0 10 10 0 10 10 10 10 0 0 0 % A
% Cys: 0 0 20 0 0 30 0 0 0 0 0 0 0 90 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 10 0 0 10 0 0 0 0 60 0 10 % F
% Gly: 10 0 0 0 20 0 0 0 0 20 0 0 0 0 0 % G
% His: 0 0 0 10 10 0 0 0 0 0 0 70 20 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 30 0 0 0 10 10 0 0 0 10 0 0 10 % K
% Leu: 0 0 0 0 20 20 20 20 10 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % N
% Pro: 10 0 0 30 20 0 40 40 70 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 20 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 40 20 0 0 10 10 0 0 20 10 0 0 0 60 % R
% Ser: 30 10 10 0 0 10 0 20 0 50 20 10 0 0 10 % S
% Thr: 10 10 0 20 0 0 10 0 0 0 50 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 0 0 0 0 10 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _