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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC22 All Species: 33.94
Human Site: T215 Identified Species: 82.96
UniProt: Q8N966 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N966 NP_777636.2 263 29100 T215 L L I L R G Q T R H Q V R K G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094840 263 29109 T215 L L I L R G Q T R H Q V R K G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A0PK84 263 29299 T215 L L I L R G Q T R Y Q V R K G
Rat Rattus norvegicus Q2TGI8 263 29230 T215 L L I L R G Q T R Y Q V R K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505597 271 29672 T223 L L I L R G Q T R H Q V R K G
Chicken Gallus gallus XP_426450 275 30622 T227 L L I L R G Q T Q Y Q V R K G
Frog Xenopus laevis Q5FWL7 338 39422 S303 P M R M A C E S R N P L L A A
Zebra Danio Brachydanio rerio XP_001340992 276 31149 T221 L L V A R G Q T W C E L Q K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190341 283 32925 T223 A L I L R G Q T T R E W R K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RWM9 429 49597 T300 W L V Y C G T T T N E S M K W
Conservation
Percent
Protein Identity: 100 N.A. 99.2 N.A. N.A. 92.4 92.7 N.A. 80.4 76.3 20.4 47 N.A. N.A. N.A. N.A. 28.2
Protein Similarity: 100 N.A. 99.2 N.A. N.A. 96.5 96.9 N.A. 86.3 86.9 33.4 63 N.A. N.A. N.A. N.A. 45.9
P-Site Identity: 100 N.A. 100 N.A. N.A. 93.3 93.3 N.A. 100 86.6 6.6 53.3 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 100 100 46.6 80 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 34.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 0 0 0 0 0 0 0 0 10 10 % A
% Cys: 0 0 0 0 10 10 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 30 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 90 0 0 0 0 0 0 0 0 80 % G
% His: 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 % H
% Ile: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 % K
% Leu: 70 90 0 70 0 0 0 0 0 0 0 20 10 0 0 % L
% Met: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 80 0 10 0 60 0 10 0 0 % Q
% Arg: 0 0 10 0 80 0 0 0 60 10 0 0 70 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 90 20 0 0 0 0 0 0 % T
% Val: 0 0 20 0 0 0 0 0 0 0 0 60 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 10 0 0 10 0 0 10 % W
% Tyr: 0 0 0 10 0 0 0 0 0 30 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _