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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC89 All Species: 23.64
Human Site: S74 Identified Species: 52
UniProt: Q8N998 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N998 NP_689936.1 374 43809 S74 R S R I E E Q S Q L I C I L K
Chimpanzee Pan troglodytes P61584 1003 117506 H351 K A R L T D K H Q S I E E A K
Rhesus Macaque Macaca mulatta XP_001100469 374 43828 S74 R S R I E D Q S Q L I C I L K
Dog Lupus familis XP_533988 370 43364 S70 C S R I Q E Q S Q L I C I L K
Cat Felis silvestris
Mouse Mus musculus Q9DA73 370 43222 S70 R S R I Q E Q S Q L I C I L K
Rat Rattus norvegicus B2RZ86 370 43435 S70 R S R I Q E Q S Q L I C I L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512805 469 53370 S172 R S R I L E Q S Q L I C I L K
Chicken Gallus gallus
Frog Xenopus laevis Q7ZW57 334 39474 Q56 K Q R A D E T Q I K W Q H L E
Zebra Danio Brachydanio rerio A8WG43 354 42138 L68 K R R A D E M L L R C Q A L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781766 342 40404 S66 L K Q R A D E S L L K A Q T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S304 707 80536 A166 P D V A Q L E A Q V K S L L A
Conservation
Percent
Protein Identity: 100 20.4 94.9 82 N.A. 77.2 77.8 N.A. 50.1 N.A. 34.7 40.3 N.A. N.A. N.A. N.A. 35.8
Protein Similarity: 100 29.7 97.5 91.1 N.A. 87.1 87.4 N.A. 63.7 N.A. 57.2 63.3 N.A. N.A. N.A. N.A. 59.3
P-Site Identity: 100 26.6 93.3 86.6 N.A. 93.3 93.3 N.A. 93.3 N.A. 20 20 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 60 100 93.3 N.A. 100 100 N.A. 93.3 N.A. 40 40 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 21.6
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 36.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 28 10 0 0 10 0 0 0 10 10 10 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 10 55 0 0 0 % C
% Asp: 0 10 0 0 19 28 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 19 64 19 0 0 0 0 10 10 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 55 0 0 0 0 10 0 64 0 55 0 0 % I
% Lys: 28 10 0 0 0 0 10 0 0 10 19 0 0 0 64 % K
% Leu: 10 0 0 10 10 10 0 10 19 64 0 0 10 82 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 10 0 37 0 55 10 73 0 0 19 10 0 0 % Q
% Arg: 46 10 82 10 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 55 0 0 0 0 0 64 0 10 0 10 0 0 0 % S
% Thr: 0 0 0 0 10 0 10 0 0 0 0 0 0 10 0 % T
% Val: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _