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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1A
All Species:
8.48
Human Site:
S243
Identified Species:
23.33
UniProt:
Q8N9B8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9B8
NP_660356.2
481
54556
S243
E
D
L
M
Q
I
V
S
H
M
D
S
L
D
N
Chimpanzee
Pan troglodytes
XP_001153789
469
53111
K231
F
V
Q
A
F
V
N
K
D
P
L
A
S
T
K
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
V229
E
E
F
V
Q
A
F
V
N
K
D
P
L
A
S
Dog
Lupus familis
XP_534955
519
58998
S281
E
D
L
M
Q
I
V
S
H
M
D
S
R
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZL7
473
55255
Q235
E
F
V
Q
A
F
V
Q
K
D
P
L
D
N
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
S284
E
D
L
M
Q
I
V
S
H
M
D
S
L
D
N
Chicken
Gallus gallus
XP_414615
480
55173
V242
E
E
F
V
Q
A
F
V
H
K
D
P
L
D
G
Frog
Xenopus laevis
NP_001086251
419
48694
C191
D
S
L
D
N
H
K
C
R
S
D
V
T
K
T
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
Q276
E
F
V
Q
A
F
V
Q
K
D
P
L
D
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.6
55
87.2
N.A.
59.2
N.A.
N.A.
78.5
54.6
70.2
56
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71
71.3
89.7
N.A.
75.8
N.A.
N.A.
85
70.2
81
72.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
26.6
86.6
N.A.
13.3
N.A.
N.A.
100
40
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
53.3
86.6
N.A.
33.3
N.A.
N.A.
100
53.3
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
23
23
0
0
0
0
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
12
34
0
12
0
0
0
0
12
23
67
0
23
45
23
% D
% Glu:
78
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
12
23
23
0
12
23
23
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
12
0
0
45
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
12
23
23
0
0
0
12
23
% K
% Leu:
0
0
45
0
0
0
0
0
0
0
12
23
45
0
0
% L
% Met:
0
0
0
34
0
0
0
0
0
34
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
12
0
12
0
0
0
0
23
23
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
23
23
0
0
0
% P
% Gln:
0
0
12
23
56
0
0
23
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% R
% Ser:
0
12
0
0
0
0
0
34
0
12
0
34
12
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
12
% T
% Val:
0
12
23
23
0
12
56
23
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _