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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGSF22
All Species:
14.85
Human Site:
T554
Identified Species:
54.44
UniProt:
Q8N9C0
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9C0
NP_775859
903
100400
T554
L
K
D
G
K
E
I
T
D
L
P
G
M
Q
I
Chimpanzee
Pan troglodytes
XP_508322
903
100375
T554
L
K
D
G
K
E
I
T
D
L
P
G
V
Q
I
Rhesus Macaque
Macaca mulatta
XP_001096645
903
100474
T554
L
K
D
G
K
E
I
T
D
L
P
G
M
Q
I
Dog
Lupus familis
XP_542527
1260
140300
T553
L
K
D
G
K
E
I
T
D
L
P
G
V
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3KNY0
1267
139421
V606
R
K
D
G
N
E
V
V
G
G
D
H
K
G
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520307
429
48489
S108
F
R
A
R
V
T
G
S
P
K
P
T
V
T
W
Chicken
Gallus gallus
Q90688
1272
142270
E742
I
I
E
G
A
E
K
E
D
E
G
V
Y
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
65.3
N.A.
24.7
N.A.
N.A.
38.3
21.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.4
68.3
N.A.
40.1
N.A.
N.A.
42.1
37.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
33.3
N.A.
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
N.A.
N.A.
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
15
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
72
0
0
0
0
0
72
0
15
0
0
0
0
% D
% Glu:
0
0
15
0
0
86
0
15
0
15
0
0
0
0
0
% E
% Phe:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
86
0
0
15
0
15
15
15
58
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
15
15
0
0
0
0
58
0
0
0
0
0
0
0
72
% I
% Lys:
0
72
0
0
58
0
15
0
0
15
0
0
15
0
0
% K
% Leu:
58
0
0
0
0
0
0
0
0
58
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
72
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% Q
% Arg:
15
15
0
15
0
0
0
0
0
0
0
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
15
0
58
0
0
0
15
0
15
0
% T
% Val:
0
0
0
0
15
0
15
15
0
0
0
15
43
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _