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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133A
All Species:
22.12
Human Site:
S106
Identified Species:
54.07
UniProt:
Q8N9E0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9E0
NP_775969.1
248
28941
S106
K
K
S
C
R
S
S
S
S
S
S
S
S
D
S
Chimpanzee
Pan troglodytes
XP_519200
223
25539
R103
K
E
K
K
K
S
G
R
Y
S
S
S
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001085869
248
28870
S106
K
K
S
C
R
S
S
S
S
S
S
S
S
D
S
Dog
Lupus familis
XP_851208
250
29108
S106
K
K
S
C
R
S
S
S
S
S
S
S
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
S106
K
K
S
G
R
Y
S
S
S
S
S
S
S
S
D
Rat
Rattus norvegicus
Q505I5
245
28015
S106
K
K
S
G
R
Y
S
S
S
S
S
S
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
R123
K
K
R
K
K
K
Y
R
P
H
K
S
S
E
G
Chicken
Gallus gallus
Q5ZLM8
250
28336
S106
K
K
S
S
R
L
S
S
S
S
S
S
S
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
S120
H
S
S
S
S
S
S
S
S
S
S
S
D
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
N60
A
F
W
E
D
K
I
N
I
K
F
R
E
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.7
92.3
90
N.A.
76.6
76.2
N.A.
48
73.1
N.A.
58.6
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
81.4
94.3
94.4
N.A.
85
85
N.A.
57.6
83.1
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
46.6
100
100
N.A.
73.3
73.3
N.A.
26.6
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
60
100
100
N.A.
73.3
73.3
N.A.
40
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
10
40
20
% D
% Glu:
0
10
0
10
0
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
10
0
0
0
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
80
70
10
20
20
20
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
60
0
0
20
0
0
0
10
0
0
0
% R
% Ser:
0
10
70
20
10
50
70
70
70
80
80
90
80
50
60
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
10
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _