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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133A
All Species:
9.7
Human Site:
S120
Identified Species:
23.7
UniProt:
Q8N9E0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9E0
NP_775969.1
248
28941
S120
S
S
S
S
S
S
D
S
E
D
E
E
K
K
Q
Chimpanzee
Pan troglodytes
XP_519200
223
25539
S117
S
S
S
D
S
S
S
S
S
S
D
S
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001085869
248
28870
S120
S
S
S
S
S
S
D
S
E
D
E
E
K
K
Q
Dog
Lupus familis
XP_851208
250
29108
E120
S
S
S
S
S
D
S
E
N
E
E
K
K
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
D120
D
S
S
S
S
S
S
D
S
E
D
E
D
K
K
Rat
Rattus norvegicus
Q505I5
245
28015
D120
D
S
S
S
S
S
S
D
S
E
E
E
D
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
S137
G
S
G
S
E
S
E
S
D
G
K
V
N
W
R
Chicken
Gallus gallus
Q5ZLM8
250
28336
A120
S
S
D
S
S
S
S
A
S
D
S
E
D
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
A134
S
S
S
S
S
S
D
A
E
D
D
D
E
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
Q74
L
R
K
T
R
E
K
Q
L
G
S
S
S
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.7
92.3
90
N.A.
76.6
76.2
N.A.
48
73.1
N.A.
58.6
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
81.4
94.3
94.4
N.A.
85
85
N.A.
57.6
83.1
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
40
100
46.6
N.A.
46.6
53.3
N.A.
26.6
46.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
60
100
66.6
N.A.
66.6
66.6
N.A.
53.3
60
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
10
10
0
10
30
20
10
40
30
10
30
10
20
% D
% Glu:
0
0
0
0
10
10
10
10
30
30
40
50
20
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
20
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
10
10
30
60
30
% K
% Leu:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
20
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
60
90
70
80
80
80
50
40
40
10
20
20
10
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _