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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM133A All Species: 23.03
Human Site: S151 Identified Species: 56.3
UniProt: Q8N9E0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9E0 NP_775969.1 248 28941 S151 S S T H E S E S E S K E S V K
Chimpanzee Pan troglodytes XP_519200 223 25539 S145 R S H K S S E S S M S E T E S
Rhesus Macaque Macaca mulatta XP_001085869 248 28870 S151 S S T Y E S E S E S K E S V K
Dog Lupus familis XP_851208 250 29108 S150 S S T Y E S G S E S K E S V K
Cat Felis silvestris
Mouse Mus musculus Q9CVI2 245 27934 S152 S S G S D S A S D S K D G S K
Rat Rattus norvegicus Q505I5 245 28015 S152 T S V S D S D S D S K D G S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520774 262 28329 S171 G P S S D V G S V H R V S I V
Chicken Gallus gallus Q5ZLM8 250 28336 E154 S S S A S E S E S D S K D S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1A5I1 259 29813 T167 E T D S E S E T D S R E S F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793119 179 21138 S102 R E R S P S S S S S S Y Q S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.7 92.3 90 N.A. 76.6 76.2 N.A. 48 73.1 N.A. 58.6 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 81.4 94.3 94.4 N.A. 85 85 N.A. 57.6 83.1 N.A. 75.6 N.A. N.A. N.A. N.A. 55.6
P-Site Identity: 100 33.3 93.3 86.6 N.A. 46.6 40 N.A. 13.3 13.3 N.A. 46.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 40 100 93.3 N.A. 66.6 73.3 N.A. 40 26.6 N.A. 73.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 30 0 10 0 30 10 0 20 10 0 0 % D
% Glu: 10 10 0 0 40 10 40 10 30 0 0 50 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 0 10 0 0 0 20 0 0 0 0 0 20 0 0 % G
% His: 0 0 10 10 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 50 10 0 0 60 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 20 0 10 0 0 0 0 0 0 0 20 0 0 0 0 % R
% Ser: 50 70 20 50 20 80 20 80 30 70 30 0 50 40 20 % S
% Thr: 10 10 30 0 0 0 0 10 0 0 0 0 10 0 10 % T
% Val: 0 0 10 0 0 10 0 0 10 0 0 10 0 30 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 20 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _