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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM133A All Species: 6.06
Human Site: S241 Identified Species: 14.81
UniProt: Q8N9E0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9E0 NP_775969.1 248 28941 S241 S K K K K K K S G S S H K S R
Chimpanzee Pan troglodytes XP_519200 223 25539
Rhesus Macaque Macaca mulatta XP_001085869 248 28870 H230 K K K K K K Q H K K R S K X X
Dog Lupus familis XP_851208 250 29108 S243 S K K K K K K S G S S H K S G
Cat Felis silvestris
Mouse Mus musculus Q9CVI2 245 27934 A237 S K K K K K K A A S S S S D S
Rat Rattus norvegicus Q505I5 245 28015 A237 S K K K K K K A A S S S S D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520774 262 28329 S249 A S Q A S S P S P S A K R F P
Chicken Gallus gallus Q5ZLM8 250 28336 A242 S K K K K K K A A G S N S D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1A5I1 259 29813
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793119 179 21138
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.7 92.3 90 N.A. 76.6 76.2 N.A. 48 73.1 N.A. 58.6 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 81.4 94.3 94.4 N.A. 85 85 N.A. 57.6 83.1 N.A. 75.6 N.A. N.A. N.A. N.A. 55.6
P-Site Identity: 100 0 40 93.3 N.A. 60 60 N.A. 13.3 53.3 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 0 46.6 93.3 N.A. 66.6 66.6 N.A. 40 66.6 N.A. 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 30 30 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 20 10 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 20 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 60 60 60 60 60 50 0 10 10 0 10 30 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 10 % P
% Gln: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 10 % R
% Ser: 50 10 0 0 10 10 0 30 0 50 50 30 30 20 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _