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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133A
All Species:
6.06
Human Site:
S241
Identified Species:
14.81
UniProt:
Q8N9E0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9E0
NP_775969.1
248
28941
S241
S
K
K
K
K
K
K
S
G
S
S
H
K
S
R
Chimpanzee
Pan troglodytes
XP_519200
223
25539
Rhesus Macaque
Macaca mulatta
XP_001085869
248
28870
H230
K
K
K
K
K
K
Q
H
K
K
R
S
K
X
X
Dog
Lupus familis
XP_851208
250
29108
S243
S
K
K
K
K
K
K
S
G
S
S
H
K
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
A237
S
K
K
K
K
K
K
A
A
S
S
S
S
D
S
Rat
Rattus norvegicus
Q505I5
245
28015
A237
S
K
K
K
K
K
K
A
A
S
S
S
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
S249
A
S
Q
A
S
S
P
S
P
S
A
K
R
F
P
Chicken
Gallus gallus
Q5ZLM8
250
28336
A242
S
K
K
K
K
K
K
A
A
G
S
N
S
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.7
92.3
90
N.A.
76.6
76.2
N.A.
48
73.1
N.A.
58.6
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
81.4
94.3
94.4
N.A.
85
85
N.A.
57.6
83.1
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
0
40
93.3
N.A.
60
60
N.A.
13.3
53.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
46.6
93.3
N.A.
66.6
66.6
N.A.
40
66.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
30
30
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
60
60
60
60
60
50
0
10
10
0
10
30
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% R
% Ser:
50
10
0
0
10
10
0
30
0
50
50
30
30
20
20
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _