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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133A
All Species:
4.55
Human Site:
T53
Identified Species:
11.11
UniProt:
Q8N9E0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.56
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9E0
NP_775969.1
248
28941
T53
K
Q
L
E
N
K
K
T
G
S
K
A
L
A
E
Chimpanzee
Pan troglodytes
XP_519200
223
25539
K53
E
Q
L
E
K
K
K
K
G
S
K
A
L
A
E
Rhesus Macaque
Macaca mulatta
XP_001085869
248
28870
T53
K
Q
L
E
N
K
K
T
G
S
K
A
L
A
E
Dog
Lupus familis
XP_851208
250
29108
K53
K
Q
L
E
N
K
K
K
G
S
K
A
L
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
K53
E
Q
L
E
K
K
K
K
G
S
K
A
L
A
E
Rat
Rattus norvegicus
Q505I5
245
28015
K53
E
Q
L
E
K
K
K
K
G
S
K
A
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
E70
E
K
L
L
G
G
S
E
S
S
S
K
K
K
E
Chicken
Gallus gallus
Q5ZLM8
250
28336
K53
E
Q
L
E
K
K
K
K
G
S
R
A
L
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
K53
E
Q
L
E
K
K
R
K
G
S
R
A
L
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
A13
N
P
I
A
A
A
R
A
S
G
P
R
P
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.7
92.3
90
N.A.
76.6
76.2
N.A.
48
73.1
N.A.
58.6
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
81.4
94.3
94.4
N.A.
85
85
N.A.
57.6
83.1
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
80
100
93.3
N.A.
80
80
N.A.
20
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
86.6
100
93.3
N.A.
86.6
86.6
N.A.
33.3
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
0
10
0
0
0
80
0
80
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
60
0
0
80
0
0
0
10
0
0
0
0
0
0
80
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
80
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
30
10
0
0
50
80
70
60
0
0
60
10
10
10
0
% K
% Leu:
0
0
90
10
0
0
0
0
0
0
0
0
80
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
80
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
20
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
20
90
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _