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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZIC4
All Species:
14.85
Human Site:
S24
Identified Species:
36.3
UniProt:
Q8N9L1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9L1
NP_115529.2
334
36567
S24
R
N
T
L
K
E
S
S
S
S
S
G
H
H
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110770
352
38335
S42
R
N
T
L
K
E
S
S
S
S
S
G
H
H
G
Dog
Lupus familis
XP_542824
335
36529
S24
R
N
S
L
K
E
S
S
S
S
S
G
H
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61467
341
37418
G31
T
L
F
V
S
T
T
G
S
S
C
G
H
H
G
Rat
Rattus norvegicus
B4F7E9
568
61629
E26
V
Q
Q
A
I
K
G
E
K
L
L
E
G
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507901
348
38127
S24
R
N
A
L
K
E
S
S
S
P
S
G
H
H
D
Chicken
Gallus gallus
P55879
663
73088
P71
Q
T
M
I
R
T
S
P
N
S
L
V
A
Y
I
Frog
Xenopus laevis
A0JC51
530
58206
L180
P
S
H
H
G
M
F
L
S
T
T
G
S
Y
H
Zebra Danio
Brachydanio rerio
Q1LYE3
623
67910
S57
A
V
T
L
V
D
G
S
T
A
Y
I
Q
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P39768
609
66219
A66
Q
D
Q
E
S
A
A
A
T
A
A
A
Y
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.9
92.8
N.A.
80.9
21.1
N.A.
72.1
23.6
44.7
22.7
N.A.
33.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
93.4
94
N.A.
84.4
30.8
N.A.
77.8
32.7
50.7
31.1
N.A.
39.4
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
40
0
N.A.
80
13.3
13.3
26.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
53.3
6.6
N.A.
80
46.6
40
46.6
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
10
10
10
0
20
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
10
0
40
0
10
0
0
0
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
20
10
0
0
0
60
10
0
40
% G
% His:
0
0
10
10
0
0
0
0
0
0
0
0
50
60
10
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
40
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
50
0
0
0
10
0
10
20
0
0
0
0
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
20
10
20
0
0
0
0
0
0
0
0
0
10
20
0
% Q
% Arg:
40
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
20
0
50
50
60
50
40
0
10
0
10
% S
% Thr:
10
10
30
0
0
20
10
0
20
10
10
0
0
0
0
% T
% Val:
10
10
0
10
10
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _