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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC57
All Species:
24.85
Human Site:
S196
Identified Species:
39.05
UniProt:
Q8N9N7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9N7
NP_694992.2
239
26754
S196
E
L
S
M
L
P
Q
S
I
L
S
D
S
Q
I
Chimpanzee
Pan troglodytes
XP_510338
165
18185
R131
P
P
Q
L
C
S
L
R
H
L
D
V
M
D
L
Rhesus Macaque
Macaca mulatta
XP_001100633
143
15863
R109
P
L
Q
L
C
S
L
R
H
L
D
V
V
D
L
Dog
Lupus familis
XP_535443
264
29530
S221
E
L
S
M
L
P
Q
S
I
L
S
D
S
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1G5
239
26742
S196
E
L
S
M
L
P
Q
S
I
L
S
D
S
Q
I
Rat
Rattus norvegicus
Q5FVI3
239
26706
S196
E
L
S
M
L
P
Q
S
I
L
S
D
S
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520403
99
10837
K65
L
D
V
V
D
L
S
K
N
Q
I
Q
S
V
P
Chicken
Gallus gallus
Q5F4C4
529
59144
T279
E
L
L
D
L
P
E
T
I
G
N
L
S
S
L
Frog
Xenopus laevis
Q6INV3
238
26715
S195
E
L
S
M
L
P
P
S
I
L
S
D
S
Q
I
Zebra Danio
Brachydanio rerio
Q6DHL5
238
26500
S195
E
L
S
S
I
P
L
S
I
L
T
D
S
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572372
238
26914
K195
Q
A
A
A
F
T
P
K
I
L
K
D
S
K
I
Honey Bee
Apis mellifera
XP_001121818
238
26897
K195
Q
L
N
A
I
P
S
K
I
L
K
N
S
K
I
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
L403
K
L
V
N
L
E
I
L
V
L
S
N
N
Q
L
Sea Urchin
Strong. purpuratus
XP_782986
212
23987
L178
L
T
D
S
H
V
S
L
L
A
L
D
G
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P0C895
374
41319
L313
L
K
T
L
P
S
A
L
F
K
M
C
L
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.1
57.3
85.9
N.A.
94.9
95.4
N.A.
31.7
22.3
76.9
69.8
N.A.
49.7
53.5
20.9
50.6
Protein Similarity:
100
69
59.4
89.3
N.A.
98.7
99.5
N.A.
38
32.5
88.6
83.2
N.A.
67.3
71.9
31.6
65.6
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
6.6
40
93.3
66.6
N.A.
33.3
40
33.3
6.6
P-Site Similarity:
100
20
26.6
100
N.A.
100
100
N.A.
13.3
66.6
93.3
86.6
N.A.
53.3
73.3
66.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
14
0
0
7
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
14
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
7
7
7
7
0
0
0
0
0
14
54
0
14
0
% D
% Glu:
47
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% G
% His:
0
0
0
0
7
0
0
0
14
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
0
7
0
60
0
7
0
0
0
47
% I
% Lys:
7
7
0
0
0
0
0
20
0
7
14
0
0
14
0
% K
% Leu:
20
67
7
20
47
7
20
20
7
74
7
7
7
0
40
% L
% Met:
0
0
0
34
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
7
7
0
0
0
0
7
0
7
14
7
7
0
% N
% Pro:
14
7
0
0
7
54
14
0
0
0
0
0
0
0
7
% P
% Gln:
14
0
14
0
0
0
27
0
0
7
0
7
0
54
0
% Q
% Arg:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% R
% Ser:
0
0
40
14
0
20
20
40
0
0
40
0
67
7
0
% S
% Thr:
0
7
7
0
0
7
0
7
0
0
7
0
0
0
0
% T
% Val:
0
0
14
7
0
7
0
0
7
0
0
14
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _