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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC57 All Species: 23.94
Human Site: T75 Identified Species: 37.62
UniProt: Q8N9N7 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9N7 NP_694992.2 239 26754 T75 S L N N N K L T V L P D E I C
Chimpanzee Pan troglodytes XP_510338 165 18185 K15 A H V E T A Q K T G V F Q L K
Rhesus Macaque Macaca mulatta XP_001100633 143 15863
Dog Lupus familis XP_535443 264 29530 T100 S L N N N K L T V L P E E L C
Cat Felis silvestris
Mouse Mus musculus Q9D1G5 239 26742 T75 S L N N N K L T V L P D E L C
Rat Rattus norvegicus Q5FVI3 239 26706 T75 S L N N N K L T V L P D E L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520403 99 10837
Chicken Gallus gallus Q5F4C4 529 59144 T159 A L S E N S L T S L P D S L D
Frog Xenopus laevis Q6INV3 238 26715 R75 L N N N R I S R L P D E L C K
Zebra Danio Brachydanio rerio Q6DHL5 238 26500 S75 I S C N K L T S L P N D I G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572372 238 26914 E75 L S G N R L V E L N E V V G E
Honey Bee Apis mellifera XP_001121818 238 26897 T75 V N H N K L T T L P E A L G A
Nematode Worm Caenorhab. elegans Q22875 559 62465 T132 G L S E N A L T S L P D S L A
Sea Urchin Strong. purpuratus XP_782986 212 23987 T62 F T L K K L D T L Y L C G N R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P0C895 374 41319 S192 G N G L S D E S I Q W E G I A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.1 57.3 85.9 N.A. 94.9 95.4 N.A. 31.7 22.3 76.9 69.8 N.A. 49.7 53.5 20.9 50.6
Protein Similarity: 100 69 59.4 89.3 N.A. 98.7 99.5 N.A. 38 32.5 88.6 83.2 N.A. 67.3 71.9 31.6 65.6
P-Site Identity: 100 0 0 86.6 N.A. 93.3 93.3 N.A. 0 46.6 13.3 13.3 N.A. 6.6 13.3 46.6 6.6
P-Site Similarity: 100 20 0 100 N.A. 100 100 N.A. 0 66.6 26.6 26.6 N.A. 20 26.6 60 13.3
Percent
Protein Identity: N.A. N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 14 0 0 0 0 0 7 0 0 20 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 7 0 7 27 % C
% Asp: 0 0 0 0 0 7 7 0 0 0 7 40 0 0 7 % D
% Glu: 0 0 0 20 0 0 7 7 0 0 14 20 27 0 7 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 14 0 14 0 0 0 0 0 0 7 0 0 14 20 0 % G
% His: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 7 0 0 7 0 0 0 7 14 0 % I
% Lys: 0 0 0 7 20 27 0 7 0 0 0 0 0 0 20 % K
% Leu: 14 40 7 7 0 27 40 0 34 40 7 0 14 40 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 34 54 40 0 0 0 0 7 7 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 20 40 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 7 0 0 7 0 0 % Q
% Arg: 0 0 0 0 14 0 0 7 0 0 0 0 0 0 7 % R
% Ser: 27 14 14 0 7 7 7 14 14 0 0 0 14 0 0 % S
% Thr: 0 7 0 0 7 0 14 54 7 0 0 0 0 0 0 % T
% Val: 7 0 7 0 0 0 7 0 27 0 7 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _