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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF1AD All Species: 49.39
Human Site: S52 Identified Species: 90.56
UniProt: Q8N9N8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9N8 NP_115701.2 165 19053 S52 Q G Q R F L V S M P S K Y R K
Chimpanzee Pan troglodytes XP_508567 166 19149 S52 Q G Q R F L V S M P S K Y R K
Rhesus Macaque Macaca mulatta XP_001111707 165 19065 S52 Q G Q R F L V S M P S K Y R K
Dog Lupus familis XP_533226 166 19133 S52 Q G Q R F L V S M P S K Y R K
Cat Felis silvestris
Mouse Mus musculus Q3THJ3 170 19502 S52 Q G Q R F L V S M P S K Y R K
Rat Rattus norvegicus Q5RKI6 167 19057 S52 Q G Q R F L V S M P S K Y R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6K1L7 188 21217 S52 D G S R F L A S M P P R F R H
Frog Xenopus laevis Q5HZM1 169 19095 S52 E G E R F L A S M P T K F R K
Zebra Danio Brachydanio rerio Q7SY07 172 19775 S52 S G E R F L L S M P T K F R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQ13 159 18519 S56 V D E T F L V S M P N K F R K
Honey Bee Apis mellifera XP_001120246 155 18102 S51 A G I Q Y L I S M P V K F R K
Nematode Worm Caenorhab. elegans Q23646 175 20401 S52 N G D S Y V V S M P T K F R K
Sea Urchin Strong. purpuratus XP_784016 211 24540 S52 E G D K F L I S M P T R F R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.3 96.9 N.A. 89.4 91 N.A. N.A. 48.9 62.1 59.2 N.A. 38.7 40 33.7 42.1
Protein Similarity: 100 99.4 99.3 98.1 N.A. 93.5 95.2 N.A. N.A. 63.2 76.3 72.6 N.A. 62.4 63 54.8 59.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 53.3 66.6 66.6 N.A. 60 53.3 53.3 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 66.6 93.3 93.3 N.A. 80 80 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 16 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 16 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 85 0 0 0 0 0 0 0 54 0 0 % F
% Gly: 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 8 0 0 0 16 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 85 0 0 93 % K
% Leu: 0 0 0 0 0 93 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 100 8 0 0 0 0 % P
% Gln: 47 0 47 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 70 0 0 0 0 0 0 0 16 0 100 0 % R
% Ser: 8 0 8 8 0 0 0 100 0 0 47 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 31 0 0 0 0 % T
% Val: 8 0 0 0 0 8 62 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 16 0 0 0 0 0 0 0 47 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _