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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF1AD
All Species:
24.85
Human Site:
T120
Identified Species:
45.56
UniProt:
Q8N9N8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9N8
NP_115701.2
165
19053
T120
H
N
N
R
N
R
Q
T
Q
P
E
L
P
A
E
Chimpanzee
Pan troglodytes
XP_508567
166
19149
T121
N
N
N
R
N
R
Q
T
Q
P
E
L
P
A
E
Rhesus Macaque
Macaca mulatta
XP_001111707
165
19065
T120
H
N
N
R
N
R
Q
T
Q
P
E
L
P
A
E
Dog
Lupus familis
XP_533226
166
19133
T121
N
N
N
R
N
R
Q
T
Q
P
E
L
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3THJ3
170
19502
S120
Q
N
N
M
N
R
E
S
Q
P
E
L
P
A
E
Rat
Rattus norvegicus
Q5RKI6
167
19057
S120
Q
N
N
V
N
R
E
S
Q
P
E
L
P
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6K1L7
188
21217
D120
T
P
Q
E
S
D
G
D
S
E
L
F
V
N
T
Frog
Xenopus laevis
Q5HZM1
169
19095
S120
L
V
A
K
E
K
E
S
S
G
I
Q
S
T
E
Zebra Danio
Brachydanio rerio
Q7SY07
172
19775
Q120
G
E
R
N
E
G
T
Q
K
E
R
S
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IQ13
159
18519
T111
A
I
W
P
D
K
F
T
K
K
P
V
Q
E
E
Honey Bee
Apis mellifera
XP_001120246
155
18102
D106
N
C
W
P
Q
E
F
D
E
V
S
N
S
K
Q
Nematode Worm
Caenorhab. elegans
Q23646
175
20401
G120
M
T
R
E
A
K
R
G
Q
T
S
D
K
M
I
Sea Urchin
Strong. purpuratus
XP_784016
211
24540
D120
S
R
H
Q
N
P
E
D
T
E
T
N
V
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.3
96.9
N.A.
89.4
91
N.A.
N.A.
48.9
62.1
59.2
N.A.
38.7
40
33.7
42.1
Protein Similarity:
100
99.4
99.3
98.1
N.A.
93.5
95.2
N.A.
N.A.
63.2
76.3
72.6
N.A.
62.4
63
54.8
59.2
P-Site Identity:
100
93.3
100
93.3
N.A.
73.3
73.3
N.A.
N.A.
0
6.6
0
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
6.6
33.3
13.3
N.A.
40
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
0
0
0
0
0
0
0
47
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
24
0
0
0
8
0
8
0
% D
% Glu:
0
8
0
16
16
8
31
0
8
24
47
0
8
16
62
% E
% Phe:
0
0
0
0
0
0
16
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
8
8
8
0
8
0
0
0
0
0
% G
% His:
16
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
8
0
24
0
0
16
8
0
0
8
8
8
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
8
47
0
0
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
24
47
47
8
54
0
0
0
0
0
0
16
0
8
0
% N
% Pro:
0
8
0
16
0
8
0
0
0
47
8
0
47
0
0
% P
% Gln:
16
0
8
8
8
0
31
8
54
0
0
8
8
0
8
% Q
% Arg:
0
8
16
31
0
47
8
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
0
24
16
0
16
8
16
0
0
% S
% Thr:
8
8
0
0
0
0
8
39
8
8
8
0
0
8
8
% T
% Val:
0
8
0
8
0
0
0
0
0
8
0
8
16
0
8
% V
% Trp:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _