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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF1AD
All Species:
25.15
Human Site:
T147
Identified Species:
46.11
UniProt:
Q8N9N8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9N8
NP_115701.2
165
19053
T147
D
S
D
L
F
V
N
T
N
R
R
Q
Y
H
E
Chimpanzee
Pan troglodytes
XP_508567
166
19149
T148
D
S
D
L
F
V
N
T
N
R
R
Q
Y
H
E
Rhesus Macaque
Macaca mulatta
XP_001111707
165
19065
T147
D
S
D
L
F
V
N
T
N
R
R
Q
Y
H
E
Dog
Lupus familis
XP_533226
166
19133
T148
D
S
D
L
F
V
N
T
N
R
R
Q
Y
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3THJ3
170
19502
T147
D
S
D
L
F
V
N
T
N
H
R
Q
Y
H
E
Rat
Rattus norvegicus
Q5RKI6
167
19057
T147
D
S
D
L
F
V
N
T
N
H
R
Q
Y
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6K1L7
188
21217
E147
E
E
D
G
G
D
T
E
S
S
E
E
E
E
E
Frog
Xenopus laevis
Q5HZM1
169
19095
V147
D
D
D
S
G
L
F
V
N
T
N
H
V
H
Y
Zebra Danio
Brachydanio rerio
Q7SY07
172
19775
T147
D
S
D
L
F
V
N
T
N
R
A
T
V
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IQ13
159
18519
N138
D
D
L
L
P
N
T
N
R
P
V
N
R
D
S
Honey Bee
Apis mellifera
XP_001120246
155
18102
R133
D
L
F
I
N
N
N
R
N
R
L
F
Q
N
R
Nematode Worm
Caenorhab. elegans
Q23646
175
20401
E147
E
D
E
S
E
G
E
E
T
Y
D
E
D
D
V
Sea Urchin
Strong. purpuratus
XP_784016
211
24540
N147
V
Q
V
E
C
K
D
N
K
T
M
K
E
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.3
96.9
N.A.
89.4
91
N.A.
N.A.
48.9
62.1
59.2
N.A.
38.7
40
33.7
42.1
Protein Similarity:
100
99.4
99.3
98.1
N.A.
93.5
95.2
N.A.
N.A.
63.2
76.3
72.6
N.A.
62.4
63
54.8
59.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
26.6
66.6
N.A.
13.3
26.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
33.3
33.3
66.6
N.A.
13.3
40
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
24
70
0
0
8
8
0
0
0
8
0
8
16
0
% D
% Glu:
16
8
8
8
8
0
8
16
0
0
8
16
16
8
62
% E
% Phe:
0
0
8
0
54
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
16
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
16
0
8
0
47
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% K
% Leu:
0
8
8
62
0
8
0
0
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
16
62
16
70
0
8
8
0
8
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
47
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
47
47
0
8
0
8
% R
% Ser:
0
54
0
16
0
0
0
0
8
8
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
16
54
8
16
0
8
0
0
0
% T
% Val:
8
0
8
0
0
54
0
8
0
0
8
0
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
47
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _