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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCAI
All Species:
23.03
Human Site:
Y422
Identified Species:
50.67
UniProt:
Q8N9R8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9R8
NP_001138349.1
606
70399
Y422
C
L
H
P
G
D
L
Y
P
F
T
R
K
P
L
Chimpanzee
Pan troglodytes
XP_528477
606
70379
Y422
C
L
H
P
G
D
L
Y
P
F
T
R
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001101911
437
50498
I258
L
Q
E
V
A
A
F
I
E
A
D
P
V
M
V
Dog
Lupus familis
XP_851980
734
84433
Y550
C
L
H
P
G
D
L
Y
P
F
T
R
K
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C8N2
606
70257
Y422
C
L
H
P
G
D
L
Y
P
F
T
R
K
P
L
Rat
Rattus norvegicus
XP_002726193
606
70271
Y422
C
L
H
P
G
D
L
Y
P
F
T
R
K
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425325
566
65735
R385
G
D
L
Y
P
F
T
R
K
P
L
F
I
I
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684264
565
65220
R385
G
D
L
F
P
F
T
R
K
P
L
F
I
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648024
628
71821
Y435
C
L
Y
P
G
D
L
Y
P
F
T
R
R
P
M
Honey Bee
Apis mellifera
XP_392438
564
65022
T385
P
G
D
L
Y
P
F
T
R
K
P
L
F
V
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566209
607
68616
V412
Y
I
Y
P
S
D
L
V
P
F
T
R
K
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
68.3
82.1
N.A.
97.6
97.8
N.A.
N.A.
90.9
N.A.
76.5
N.A.
50.9
53.1
N.A.
N.A.
Protein Similarity:
100
99.8
68.3
82.4
N.A.
99
99
N.A.
N.A.
92.5
N.A.
85.6
N.A.
66.8
67.6
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
0
N.A.
0
N.A.
80
0
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
6.6
N.A.
100
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% A
% Cys:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
10
0
0
64
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
19
19
0
0
64
0
19
10
0
0
% F
% Gly:
19
10
0
0
55
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
19
19
0
% I
% Lys:
0
0
0
0
0
0
0
0
19
10
0
0
55
0
0
% K
% Leu:
10
55
19
10
0
0
64
0
0
0
19
10
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
64
19
10
0
0
64
19
10
10
0
64
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
10
0
0
64
10
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
19
10
0
0
64
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
10
0
0
0
0
10
10
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
19
10
10
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _