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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCAI All Species: 18.79
Human Site: Y506 Identified Species: 41.33
UniProt: Q8N9R8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9R8 NP_001138349.1 606 70399 Y506 L W E K C Q E Y L R K I N R D
Chimpanzee Pan troglodytes XP_528477 606 70379 Y506 L W E K C Q E Y L R K I N R D
Rhesus Macaque Macaca mulatta XP_001101911 437 50498 G342 A S Q M N K P G M Q E S A D K
Dog Lupus familis XP_851980 734 84433 Y634 L W E K C Q E Y L R K I N R D
Cat Felis silvestris
Mouse Mus musculus Q8C8N2 606 70257 Y506 L W E K C Q E Y L R K I N R D
Rat Rattus norvegicus XP_002726193 606 70271 Y506 L W E K C Q E Y L R K I N R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425325 566 65735 I469 C Q D Y L R K I N R D I A Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684264 565 65220 V469 A Q E L L R K V F H D I G Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648024 628 71821 T519 H H W E R C Q T Y V D R F I T
Honey Bee Apis mellifera XP_392438 564 65022 R469 R C Q R Y I E R F L I E A C Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_566209 607 68616 F496 S D M E T D I F T K A E K L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 68.3 82.1 N.A. 97.6 97.8 N.A. N.A. 90.9 N.A. 76.5 N.A. 50.9 53.1 N.A. N.A.
Protein Similarity: 100 99.8 68.3 82.4 N.A. 99 99 N.A. N.A. 92.5 N.A. 85.6 N.A. 66.8 67.6 N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. N.A. 13.3 N.A. 13.3 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. N.A. 40 N.A. 33.3 N.A. 13.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 0 0 0 0 0 10 0 28 0 0 % A
% Cys: 10 10 0 0 46 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 10 10 0 0 10 0 0 0 0 28 0 0 10 46 % D
% Glu: 0 0 55 19 0 0 55 0 0 0 10 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 19 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % G
% His: 10 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 10 0 0 10 64 0 10 0 % I
% Lys: 0 0 0 46 0 10 19 0 0 10 46 0 10 0 10 % K
% Leu: 46 0 0 10 19 0 0 0 46 10 0 0 0 10 19 % L
% Met: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 10 0 0 0 46 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 19 19 0 0 46 10 0 0 10 0 0 0 19 10 % Q
% Arg: 10 0 0 10 10 19 0 10 0 55 0 10 0 46 0 % R
% Ser: 10 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 10 10 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % V
% Trp: 0 46 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 0 0 46 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _