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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BOLL All Species: 17.58
Human Site: S246 Identified Species: 29.74
UniProt: Q8N9W6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9W6 NP_149019.1 283 31301 S246 T S V P E P Y S D H G V Q A T
Chimpanzee Pan troglodytes XP_001169413 283 31309 S246 T S V P E P Y S D Y G V Q A T
Rhesus Macaque Macaca mulatta XP_001086915 647 70602 S610 T S V P E P Y S D H G V Q A T
Dog Lupus familis XP_545580 418 45159 S381 A S V P E P Y S D H G V Q A T
Cat Felis silvestris
Mouse Mus musculus Q924M5 281 30837 Y245 E T S V P E P Y S D H G V Q A
Rat Rattus norvegicus NP_001106841 293 32129 Y257 E A S V P E P Y S D H G V Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512796 165 18140 A129 P R S S L M P A A G T M Y L R
Chicken Gallus gallus Q804A9 289 32698 S251 R S I Q T V V S C L F N P E N
Frog Xenopus laevis O57437 286 32279 C248 S T Q T I V S C L F D P A N K
Zebra Danio Brachydanio rerio Q9YGW7 229 25529 T193 V P M N Y A Q T T Y A Y Q Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24207 228 24663 S192 Q N Y Q E N H S P L L H S P T
Honey Bee Apis mellifera XP_001122634 254 27071 Q218 L Y M P Q Q Y Q Y S P M P T N
Nematode Worm Caenorhab. elegans Q20870 499 56134 A325 P H P Y Q Q F A Q S G V Y M N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q03251 169 16560 G133 E R R S G G Y G S G G G G G G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 43.2 64.8 N.A. 91.8 88.4 N.A. 51.9 30.7 26.5 32.5 N.A. 34.2 36.4 23.6 N.A.
Protein Similarity: 100 100 43.4 65.7 N.A. 94.6 90.7 N.A. 54 47.7 43 44.8 N.A. 50.1 54 34.4 N.A.
P-Site Identity: 100 93.3 100 93.3 N.A. 0 0 N.A. 0 13.3 0 6.6 N.A. 20 13.3 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 6.6 6.6 N.A. 13.3 20 13.3 26.6 N.A. 33.3 33.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 29.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 15 8 0 8 0 8 29 15 % A
% Cys: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 29 15 8 0 0 0 0 % D
% Glu: 22 0 0 0 36 15 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % F
% Gly: 0 0 0 0 8 8 0 8 0 15 43 22 8 8 8 % G
% His: 0 8 0 0 0 0 8 0 0 22 15 8 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 8 0 0 0 8 0 0 0 8 15 8 0 0 8 0 % L
% Met: 0 0 15 0 0 8 0 0 0 0 0 15 0 8 0 % M
% Asn: 0 8 0 8 0 8 0 0 0 0 0 8 0 8 22 % N
% Pro: 15 8 8 36 15 29 22 0 8 0 8 8 15 8 8 % P
% Gln: 8 0 8 15 15 15 8 8 8 0 0 0 36 15 0 % Q
% Arg: 8 15 8 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 36 22 15 0 0 8 43 22 15 0 0 8 0 0 % S
% Thr: 22 15 0 8 8 0 0 8 8 0 8 0 0 8 36 % T
% Val: 8 0 29 15 0 15 8 0 0 0 0 36 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 8 8 0 43 15 8 15 0 8 15 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _