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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM181A
All Species:
8.79
Human Site:
S149
Identified Species:
24.17
UniProt:
Q8N9Y4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9Y4
NP_612353.2
354
38724
S149
L
L
D
L
G
P
D
S
S
P
G
G
G
G
G
Chimpanzee
Pan troglodytes
XP_001143456
372
40084
S167
L
L
D
L
G
P
D
S
S
P
G
G
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001095747
426
42685
G194
A
A
P
V
A
G
L
G
G
A
G
T
G
G
A
Dog
Lupus familis
XP_855178
456
48864
S251
P
L
G
S
G
H
D
S
S
T
G
E
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80VF6
417
42418
S159
A
A
A
A
S
L
Q
S
R
S
L
A
A
L
F
Rat
Rattus norvegicus
NP_001102620
419
42855
S189
A
G
G
A
V
A
A
S
V
P
G
L
G
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511042
314
33642
G149
A
L
R
D
Q
S
P
G
A
A
R
P
D
H
V
Chicken
Gallus gallus
XP_421336
288
31345
D124
N
P
E
T
N
R
P
D
Q
V
P
M
R
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664638
321
35276
E150
P
A
K
D
V
R
G
E
R
A
K
K
P
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
23.7
65.7
N.A.
23.2
22.9
N.A.
56.2
49.7
N.A.
22.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.4
33.5
69.7
N.A.
34
34.3
N.A.
62.9
57.6
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
60
N.A.
6.6
26.6
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
60
N.A.
6.6
26.6
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
34
12
23
12
12
12
0
12
34
0
12
12
12
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
23
0
0
34
12
0
0
0
0
12
0
0
% D
% Glu:
0
0
12
0
0
0
0
12
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
23
0
34
12
12
23
12
0
56
23
56
45
34
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
12
12
0
12
0
% K
% Leu:
23
45
0
23
0
12
12
0
0
0
12
12
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
12
12
0
0
23
23
0
0
34
12
12
12
12
0
% P
% Gln:
0
0
0
0
12
0
12
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
23
0
0
23
0
12
0
12
0
12
% R
% Ser:
0
0
0
12
12
12
0
56
34
12
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
12
0
12
0
0
0
% T
% Val:
0
0
0
12
23
0
0
0
12
12
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _