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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FSIP1 All Species: 12.73
Human Site: S421 Identified Species: 31.11
UniProt: Q8NA03 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NA03 NP_689810.3 581 66121 S421 E C I L K Q K S I I K L S S E
Chimpanzee Pan troglodytes XP_001138937 581 66285 S421 E C I L K Q K S I I K L S S E
Rhesus Macaque Macaca mulatta XP_001092358 581 66088 S421 E C I V K Q K S I I K L S S E
Dog Lupus familis XP_535430 605 68047 Q419 L D E C I L K Q K S V T R L S
Cat Felis silvestris
Mouse Mus musculus Q9D3V5 435 48950 R278 I E L A K H S R S P V V M V E
Rat Rattus norvegicus Q66H16 438 49550 V281 A K S S R S P V V M V E G E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421204 609 68439 T445 E C M Q P Q R T I S N V T M P
Frog Xenopus laevis A1L2Y1 459 52051 E302 D F I Q R N I E L A K D A G A
Zebra Danio Brachydanio rerio Q566N9 374 42572 C217 S R P E P E E C V E A A G H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785087 670 74016 T513 R L Q Q T P S T L Q S N Q S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 92.4 70.9 N.A. 45 44.5 N.A. N.A. 36.4 20.4 20.1 N.A. N.A. N.A. N.A. 23.7
Protein Similarity: 100 98.6 95.5 80.3 N.A. 56.2 55.4 N.A. N.A. 56.6 38.9 36.3 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 100 93.3 6.6 N.A. 13.3 0 N.A. N.A. 26.6 13.3 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 6.6 N.A. 26.6 26.6 N.A. N.A. 60 40 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 0 10 10 10 10 0 20 % A
% Cys: 0 40 0 10 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 40 10 10 10 0 10 10 10 0 10 0 10 0 10 40 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 20 10 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % H
% Ile: 10 0 40 0 10 0 10 0 40 30 0 0 0 0 0 % I
% Lys: 0 10 0 0 40 0 40 0 10 0 40 0 0 0 10 % K
% Leu: 10 10 10 20 0 10 0 0 20 0 0 30 0 10 0 % L
% Met: 0 0 10 0 0 0 0 0 0 10 0 0 10 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 10 0 20 10 10 0 0 10 0 0 0 0 10 % P
% Gln: 0 0 10 30 0 40 0 10 0 10 0 0 10 0 0 % Q
% Arg: 10 10 0 0 20 0 10 10 0 0 0 0 10 0 0 % R
% Ser: 10 0 10 10 0 10 20 30 10 20 10 0 30 40 20 % S
% Thr: 0 0 0 0 10 0 0 20 0 0 0 10 10 0 0 % T
% Val: 0 0 0 10 0 0 0 10 20 0 30 20 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _