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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD2A
All Species:
30
Human Site:
Y505
Identified Species:
73.33
UniProt:
Q8NA29
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA29
NP_001129965.1
543
60170
Y505
G
L
L
L
F
K
M
Y
P
I
D
E
E
R
R
Chimpanzee
Pan troglodytes
XP_001171678
543
60136
Y505
G
L
L
L
F
K
M
Y
P
I
D
E
E
R
R
Rhesus Macaque
Macaca mulatta
XP_001112197
412
45967
R382
P
I
D
E
E
R
R
R
Q
N
K
K
A
L
Q
Dog
Lupus familis
XP_532546
529
58216
Y491
G
L
L
L
F
K
L
Y
P
I
D
E
E
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DA75
534
58966
Y496
G
L
L
L
F
K
L
Y
P
I
D
E
E
K
R
Rat
Rattus norvegicus
NP_001100153
534
58661
Y496
G
L
L
L
F
K
L
Y
P
I
D
E
E
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509671
547
60725
Y510
G
L
S
V
L
I
F
Y
P
I
T
E
E
R
R
Chicken
Gallus gallus
XP_417826
569
62938
Y533
G
L
L
L
F
K
L
Y
P
I
D
E
E
K
R
Frog
Xenopus laevis
NP_001093350
524
58549
Y489
G
L
L
L
F
I
L
Y
P
I
N
E
E
K
R
Zebra Danio
Brachydanio rerio
Q6DEJ6
523
57860
I491
L
I
F
I
S
Y
P
I
N
E
E
K
R
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
73.6
86.7
N.A.
83.2
84.9
N.A.
39.1
63.7
67.4
62.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
75.1
90.9
N.A.
89.5
90.4
N.A.
57.4
74.8
79.3
77.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
86.6
86.6
N.A.
60
86.6
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
66.6
100
93.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
60
0
0
0
0
% D
% Glu:
0
0
0
10
10
0
0
0
0
10
10
80
80
0
0
% E
% Phe:
0
0
10
0
70
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
10
0
20
0
10
0
80
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
60
0
0
0
0
10
20
0
50
0
% K
% Leu:
10
80
70
70
10
0
50
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
80
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% Q
% Arg:
0
0
0
0
0
10
10
10
0
0
0
0
10
30
80
% R
% Ser:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _