KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQUB
All Species:
19.7
Human Site:
Y595
Identified Species:
48.15
UniProt:
Q8NA54
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA54
NP_849149.3
791
92581
Y595
P
Q
D
P
L
K
F
Y
K
K
I
Y
F
C
H
Chimpanzee
Pan troglodytes
XP_001147235
791
92566
Y595
P
Q
D
P
L
K
F
Y
K
K
I
Y
F
C
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532536
805
93294
S606
P
Q
D
P
L
M
F
S
K
K
V
D
F
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDK3
788
92111
Y591
P
Q
D
P
L
K
F
Y
D
T
I
Y
F
C
H
Rat
Rattus norvegicus
Q45GW3
790
91804
Y593
P
Q
D
P
L
K
F
Y
D
K
I
Y
F
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507699
857
98749
Y662
P
Q
D
P
L
K
L
Y
K
N
V
H
F
C
R
Chicken
Gallus gallus
XP_415998
704
80925
P511
I
K
I
P
K
F
N
P
E
V
A
K
I
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666923
750
86869
D557
R
V
P
R
D
P
A
D
L
K
K
N
I
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651037
706
83867
Q513
F
F
D
L
I
K
F
Q
K
G
E
P
K
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794435
877
98995
P679
A
A
R
L
L
K
V
P
Q
D
P
S
T
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
75.6
N.A.
69.6
69.4
N.A.
52.2
47.4
N.A.
45.8
N.A.
27.5
N.A.
N.A.
41.7
Protein Similarity:
100
99.8
N.A.
86.5
N.A.
83.6
83.8
N.A.
68.4
62.8
N.A.
63.5
N.A.
45.6
N.A.
N.A.
60.2
P-Site Identity:
100
100
N.A.
66.6
N.A.
86.6
93.3
N.A.
66.6
6.6
N.A.
6.6
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
73.3
N.A.
86.6
93.3
N.A.
80
20
N.A.
6.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% C
% Asp:
0
0
70
0
10
0
0
10
20
10
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% E
% Phe:
10
10
0
0
0
10
60
0
0
0
0
0
60
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
40
% H
% Ile:
10
0
10
0
10
0
0
0
0
0
40
0
20
0
0
% I
% Lys:
0
10
0
0
10
70
0
0
50
50
10
10
10
0
10
% K
% Leu:
0
0
0
20
70
0
10
0
10
0
0
0
0
20
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% N
% Pro:
60
0
10
70
0
10
0
20
0
0
10
10
0
0
0
% P
% Gln:
0
60
0
0
0
0
0
10
10
0
0
0
0
10
0
% Q
% Arg:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
40
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
10
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
40
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _