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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP8
All Species:
7.88
Human Site:
S99
Identified Species:
17.33
UniProt:
Q8NA92
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA92
NP_689871.1
274
30082
S99
K
S
Q
R
R
T
R
S
T
Q
K
P
V
S
P
Chimpanzee
Pan troglodytes
XP_516210
686
73181
H206
K
K
R
G
A
G
G
H
G
R
T
R
R
K
D
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
R99
K
S
Q
Q
R
T
R
R
T
Q
K
P
V
S
P
Dog
Lupus familis
XP_541680
871
94748
S99
K
R
Q
Q
S
S
R
S
T
E
K
P
V
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
H97
K
K
R
G
A
G
G
H
G
H
A
R
R
K
T
Rat
Rattus norvegicus
Q642B6
569
62388
H97
K
K
R
G
A
G
G
H
G
P
A
R
R
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507681
214
23009
P71
T
V
R
R
A
G
S
P
G
G
R
S
F
P
R
Chicken
Gallus gallus
Q5ZHN5
413
46679
S99
E
K
G
S
S
Q
N
S
P
Q
E
I
R
R
E
Frog
Xenopus laevis
Q0IHI7
372
42347
L99
Q
D
I
A
E
L
E
L
T
I
K
E
G
T
Q
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
T82
N
A
V
P
S
L
F
T
L
Q
T
Q
D
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
T96
F
K
P
K
K
T
K
T
T
K
Q
K
K
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
91.6
22.9
N.A.
22.5
23
N.A.
25.5
25.4
25.2
24
N.A.
N.A.
N.A.
N.A.
20.6
Protein Similarity:
100
28.1
94.5
26.7
N.A.
31.9
32.8
N.A.
36.1
38.9
37.6
39.7
N.A.
N.A.
N.A.
N.A.
34.7
P-Site Identity:
100
6.6
86.6
53.3
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
93.3
73.3
N.A.
13.3
13.3
N.A.
20
26.6
26.6
20
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
37
0
0
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% D
% Glu:
10
0
0
0
10
0
10
0
0
10
10
10
0
19
10
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% F
% Gly:
0
0
10
28
0
37
28
0
37
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
28
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
10
% I
% Lys:
55
46
0
10
10
0
10
0
0
10
37
10
10
28
0
% K
% Leu:
0
0
0
0
0
19
0
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
10
10
10
0
28
0
19
19
% P
% Gln:
10
0
28
19
0
10
0
0
0
37
10
10
0
0
10
% Q
% Arg:
0
10
37
19
19
0
28
10
0
10
10
28
37
10
10
% R
% Ser:
0
19
0
10
28
10
10
28
0
0
0
10
0
19
10
% S
% Thr:
10
0
0
0
0
28
0
19
46
0
19
0
0
10
19
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _