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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP8
All Species:
5.45
Human Site:
T226
Identified Species:
12
UniProt:
Q8NA92
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA92
NP_689871.1
274
30082
T226
R
G
L
Q
R
L
T
T
A
Q
T
L
G
P
E
Chimpanzee
Pan troglodytes
XP_516210
686
73181
E481
Q
V
E
K
K
N
G
E
L
K
S
L
R
Q
R
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
T226
R
G
L
Q
R
L
T
T
A
Q
T
L
G
P
E
Dog
Lupus familis
XP_541680
871
94748
S217
E
G
L
P
A
R
R
S
R
A
C
Y
A
C
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
E361
Q
V
E
K
K
N
G
E
L
K
S
L
R
Q
K
Rat
Rattus norvegicus
Q642B6
569
62388
E361
Q
V
E
K
K
N
G
E
L
K
S
L
R
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507681
214
23009
A172
L
G
P
G
G
T
E
A
R
A
A
G
L
G
G
Chicken
Gallus gallus
Q5ZHN5
413
46679
V203
Q
N
V
E
A
T
D
V
H
A
S
V
E
V
P
Frog
Xenopus laevis
Q0IHI7
372
42347
Q245
F
P
L
S
L
V
K
Q
T
K
Q
M
D
A
E
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
R183
T
L
Q
Q
K
C
R
R
Q
E
R
Q
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
K272
E
D
K
T
K
V
N
K
E
K
Q
L
P
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
91.6
22.9
N.A.
22.5
23
N.A.
25.5
25.4
25.2
24
N.A.
N.A.
N.A.
N.A.
20.6
Protein Similarity:
100
28.1
94.5
26.7
N.A.
31.9
32.8
N.A.
36.1
38.9
37.6
39.7
N.A.
N.A.
N.A.
N.A.
34.7
P-Site Identity:
100
6.6
100
13.3
N.A.
6.6
6.6
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
40
100
20
N.A.
46.6
40
N.A.
6.6
33.3
33.3
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
10
19
28
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
10
10
0
% D
% Glu:
19
0
28
10
0
0
10
28
10
10
0
0
10
10
28
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
37
0
10
10
0
28
0
0
0
0
10
19
10
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
28
46
0
10
10
0
46
0
0
0
0
19
% K
% Leu:
10
10
37
0
10
19
0
0
28
0
0
55
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
0
28
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
10
0
0
0
0
0
0
0
0
10
19
10
% P
% Gln:
37
0
10
28
0
0
0
10
10
19
19
10
0
28
0
% Q
% Arg:
19
0
0
0
19
10
19
10
19
0
10
0
28
0
28
% R
% Ser:
0
0
0
10
0
0
0
10
0
0
37
0
0
0
0
% S
% Thr:
10
0
0
10
0
19
19
19
10
0
19
0
0
0
0
% T
% Val:
0
28
10
0
0
19
0
10
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _