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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP8
All Species:
11.82
Human Site:
T259
Identified Species:
26
UniProt:
Q8NA92
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA92
NP_689871.1
274
30082
T259
A
Q
D
P
A
P
A
T
V
D
A
K
P
E
L
Chimpanzee
Pan troglodytes
XP_516210
686
73181
R653
E
Q
I
T
R
K
F
R
L
N
S
E
G
K
L
Rhesus Macaque
Macaca mulatta
XP_001101774
274
29830
T259
A
Q
G
P
A
P
A
T
V
D
A
K
P
E
L
Dog
Lupus familis
XP_541680
871
94748
T250
A
Q
R
P
T
P
P
T
L
D
A
K
P
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
R536
E
Q
I
T
R
K
F
R
L
N
S
E
G
K
L
Rat
Rattus norvegicus
Q642B6
569
62388
R536
Q
Q
I
T
R
K
F
R
L
N
S
E
G
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507681
214
23009
L200
W
P
A
R
G
S
E
L
T
P
R
V
R
P
E
Chicken
Gallus gallus
Q5ZHN5
413
46679
T262
S
V
E
V
Q
P
A
T
E
N
A
V
L
V
N
Frog
Xenopus laevis
Q0IHI7
372
42347
S334
A
Q
E
N
A
T
L
S
R
L
R
L
L
E
S
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
L211
Y
V
I
L
P
R
E
L
Y
E
E
L
Q
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
V335
S
V
G
D
N
H
V
V
L
K
H
R
M
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
91.6
22.9
N.A.
22.5
23
N.A.
25.5
25.4
25.2
24
N.A.
N.A.
N.A.
N.A.
20.6
Protein Similarity:
100
28.1
94.5
26.7
N.A.
31.9
32.8
N.A.
36.1
38.9
37.6
39.7
N.A.
N.A.
N.A.
N.A.
34.7
P-Site Identity:
100
13.3
93.3
73.3
N.A.
13.3
13.3
N.A.
0
26.6
26.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
46.6
93.3
80
N.A.
46.6
46.6
N.A.
0
46.6
40
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
10
0
28
0
28
0
0
0
37
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
0
28
0
0
0
10
0
% D
% Glu:
19
0
19
0
0
0
19
0
10
10
10
28
0
37
10
% E
% Phe:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
19
0
10
0
0
0
0
0
0
0
28
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
28
0
0
0
10
0
28
0
28
0
% K
% Leu:
0
0
0
10
0
0
10
19
46
10
0
19
19
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
0
37
0
0
0
0
10
% N
% Pro:
0
10
0
28
10
37
10
0
0
10
0
0
28
10
0
% P
% Gln:
10
64
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
10
28
10
0
28
10
0
19
10
10
0
0
% R
% Ser:
19
0
0
0
0
10
0
10
0
0
28
0
0
0
10
% S
% Thr:
0
0
0
28
10
10
0
37
10
0
0
0
0
0
0
% T
% Val:
0
28
0
10
0
0
10
10
19
0
0
19
0
10
19
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _