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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L2
All Species:
16.67
Human Site:
S236
Identified Species:
40.74
UniProt:
Q8NAA4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAA4
NP_203746.1
619
68998
S236
A
K
R
T
V
S
I
S
E
G
P
D
T
L
G
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
E210
N
R
L
N
A
E
N
E
K
D
S
R
R
R
Q
Rhesus Macaque
Macaca mulatta
XP_001110048
627
69946
S244
A
K
R
T
V
S
I
S
E
G
P
D
T
V
G
Dog
Lupus familis
XP_542323
614
67784
S231
A
Q
R
T
V
S
I
S
E
S
P
N
T
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAU8
623
69223
S240
A
K
R
T
V
S
I
S
E
I
P
N
T
L
E
Rat
Rattus norvegicus
XP_002725746
623
69178
S240
A
K
R
T
V
S
I
S
E
I
P
N
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512513
345
38000
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091437
622
69873
D235
A
K
E
P
L
S
F
D
H
D
D
D
I
E
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09406
534
60477
D159
T
E
K
K
T
Q
L
D
N
E
R
F
Q
L
L
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
N195
L
Y
R
L
Q
A
E
N
A
E
L
V
T
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
92.5
83.8
N.A.
82.5
81.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
N.A.
N.A.
26.4
28.5
Protein Similarity:
100
57.8
94
89
N.A.
88.5
88.1
N.A.
47.1
N.A.
55.3
N.A.
N.A.
N.A.
N.A.
48.4
49.4
P-Site Identity:
100
0
93.3
73.3
N.A.
80
80
N.A.
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
20
10
30
0
0
0
% D
% Glu:
0
10
10
0
0
10
10
10
50
20
0
0
0
10
20
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
30
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
20
0
0
10
10
0
% I
% Lys:
0
50
10
10
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
10
10
10
0
10
0
0
0
10
0
0
40
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
10
10
10
0
0
30
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
50
0
0
0
0
% P
% Gln:
0
10
0
0
10
10
0
0
0
0
0
0
10
0
10
% Q
% Arg:
0
10
60
0
0
0
0
0
0
0
10
10
10
20
0
% R
% Ser:
0
0
0
0
0
60
0
50
0
10
10
0
0
0
0
% S
% Thr:
10
0
0
50
10
0
0
0
0
0
0
0
60
0
0
% T
% Val:
0
0
0
0
50
0
0
0
0
0
0
10
0
10
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _