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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG16L2
All Species:
8.18
Human Site:
T65
Identified Species:
20
UniProt:
Q8NAA4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAA4
NP_203746.1
619
68998
T65
Q
P
E
P
N
S
V
T
P
T
T
H
Q
G
P
Chimpanzee
Pan troglodytes
XP_001150112
607
68277
P64
Q
A
E
K
H
D
V
P
N
R
H
E
I
S
P
Rhesus Macaque
Macaca mulatta
XP_001110048
627
69946
T65
Q
P
E
P
N
S
V
T
P
T
T
H
Q
G
P
Dog
Lupus familis
XP_542323
614
67784
T59
Q
P
K
P
N
D
V
T
P
A
T
L
Q
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAU8
623
69223
I68
K
S
E
P
K
D
A
I
S
T
R
H
E
D
W
Rat
Rattus norvegicus
XP_002725746
623
69178
I68
K
S
E
P
K
D
V
I
S
T
P
H
Q
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512513
345
38000
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091437
622
69873
Q64
Q
T
E
K
Y
E
P
Q
S
R
H
D
S
S
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09406
534
60477
K57
S
V
N
D
E
H
F
K
G
N
V
N
D
R
L
Sea Urchin
Strong. purpuratus
XP_781454
582
65038
Q62
H
V
Q
V
E
R
L
Q
Q
E
N
T
D
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
92.5
83.8
N.A.
82.5
81.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
N.A.
N.A.
26.4
28.5
Protein Similarity:
100
57.8
94
89
N.A.
88.5
88.1
N.A.
47.1
N.A.
55.3
N.A.
N.A.
N.A.
N.A.
48.4
49.4
P-Site Identity:
100
26.6
100
73.3
N.A.
26.6
40
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
33.3
100
80
N.A.
40
46.6
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
40
0
0
0
0
0
10
20
20
0
% D
% Glu:
0
0
60
0
20
10
0
0
0
10
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
30
0
% G
% His:
10
0
0
0
10
10
0
0
0
0
20
40
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
20
0
0
0
0
10
0
0
% I
% Lys:
20
0
10
20
20
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
30
0
0
0
10
10
10
10
0
0
0
% N
% Pro:
0
30
0
50
0
0
10
10
30
0
10
0
0
0
40
% P
% Gln:
50
0
10
0
0
0
0
20
10
0
0
0
40
0
20
% Q
% Arg:
0
0
0
0
0
10
0
0
0
20
10
0
0
10
0
% R
% Ser:
10
20
0
0
0
20
0
0
30
0
0
0
10
20
10
% S
% Thr:
0
10
0
0
0
0
0
30
0
40
30
10
0
0
0
% T
% Val:
0
20
0
10
0
0
50
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _