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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL17RC
All Species:
8.79
Human Site:
Y252
Identified Species:
32.22
UniProt:
Q8NAC3
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAC3
NP_116121.2
791
86240
Y252
W
S
Y
T
Q
P
R
Y
E
K
E
L
N
H
T
Chimpanzee
Pan troglodytes
XP_001148317
787
86030
Y252
W
S
Y
T
Q
P
R
Y
E
K
E
L
N
H
T
Rhesus Macaque
Macaca mulatta
XP_001092217
801
87609
Y252
W
S
Y
T
Q
P
R
Y
E
K
E
L
N
L
T
Dog
Lupus familis
XP_852620
717
78774
E229
Y
L
V
L
D
V
S
E
E
Q
R
F
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4C2
674
74411
D198
D
N
V
L
L
T
L
D
V
S
E
E
Q
D
F
Rat
Rattus norvegicus
Q6AZ51
637
70834
N161
I
P
P
G
P
E
A
N
V
R
L
C
Y
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508119
687
75342
W211
Q
S
C
W
T
L
P
W
L
N
V
S
A
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
89.5
74.2
N.A.
58.4
20.2
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
92.2
80
N.A.
67.2
32.8
N.A.
64.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
15
0
0
0
15
0
0
15
0
0
0
0
0
15
0
% D
% Glu:
0
0
0
0
0
15
0
15
58
0
58
15
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
15
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
0
0
15
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% K
% Leu:
0
15
0
29
15
15
15
0
15
0
15
43
0
29
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
15
0
15
0
0
43
0
0
% N
% Pro:
0
15
15
0
15
43
15
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
43
0
0
0
0
15
0
0
15
15
0
% Q
% Arg:
0
0
0
0
0
0
43
0
0
15
15
0
0
0
0
% R
% Ser:
0
58
0
0
0
0
15
0
0
15
0
15
0
0
15
% S
% Thr:
0
0
0
43
15
15
0
0
0
0
0
0
0
0
43
% T
% Val:
0
0
29
0
0
15
0
0
29
0
15
0
0
0
0
% V
% Trp:
43
0
0
15
0
0
0
15
0
0
0
0
0
0
15
% W
% Tyr:
15
0
43
0
0
0
0
43
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _