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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKLE1
All Species:
8.18
Human Site:
S345
Identified Species:
25.71
UniProt:
Q8NAG6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAG6
NP_689576.4
575
62235
S345
P
C
R
H
L
P
V
S
T
V
S
D
L
E
L
Chimpanzee
Pan troglodytes
XP_001173375
575
62144
S345
P
C
R
H
L
P
V
S
T
V
S
D
L
E
L
Rhesus Macaque
Macaca mulatta
XP_001114324
683
73209
S427
C
C
Q
H
P
P
V
S
I
V
S
D
L
E
L
Dog
Lupus familis
XP_852664
443
49437
W273
R
P
D
P
K
R
R
W
R
E
G
L
I
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519527
622
67527
P344
L
P
E
P
P
L
S
P
G
G
R
P
Q
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395966
443
50476
P273
L
T
K
L
K
T
S
P
S
R
K
W
R
E
G
Nematode Worm
Caenorhab. elegans
NP_492539
732
81526
L431
E
I
R
K
I
R
R
L
R
E
G
E
L
K
S
Sea Urchin
Strong. purpuratus
XP_781548
802
88988
N499
G
S
E
P
S
L
L
N
F
S
F
A
S
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
79.6
54.9
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
21
31.4
Protein Similarity:
100
98.2
81.2
60.7
N.A.
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
41.9
34.2
43
P-Site Identity:
100
100
73.3
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
100
100
80
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% A
% Cys:
13
38
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
38
0
0
13
% D
% Glu:
13
0
25
0
0
0
0
0
0
25
0
13
0
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
13
13
25
0
0
0
13
% G
% His:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
13
0
0
0
13
0
0
0
13
0
0
% I
% Lys:
0
0
13
13
25
0
0
0
0
0
13
0
0
25
0
% K
% Leu:
25
0
0
13
25
25
13
13
0
0
0
13
50
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
25
25
0
38
25
38
0
25
0
0
0
13
0
0
0
% P
% Gln:
0
0
13
0
0
0
0
0
0
0
0
0
13
13
0
% Q
% Arg:
13
0
38
0
0
25
25
0
25
13
13
0
13
0
0
% R
% Ser:
0
13
0
0
13
0
25
38
13
13
38
0
13
0
25
% S
% Thr:
0
13
0
0
0
13
0
0
25
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
38
0
0
38
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _