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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKLE1
All Species:
9.09
Human Site:
S364
Identified Species:
28.57
UniProt:
Q8NAG6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAG6
NP_689576.4
575
62235
S364
R
A
L
G
P
E
F
S
G
H
S
L
E
L
A
Chimpanzee
Pan troglodytes
XP_001173375
575
62144
S364
R
A
L
G
P
E
F
S
G
H
S
L
E
L
A
Rhesus Macaque
Macaca mulatta
XP_001114324
683
73209
S472
I
A
P
G
P
E
F
S
G
H
S
L
E
L
A
Dog
Lupus familis
XP_852664
443
49437
E291
Y
L
L
M
D
P
R
E
T
Q
D
L
P
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519527
622
67527
T378
I
E
R
H
L
P
G
T
E
E
S
A
S
D
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395966
443
50476
L291
T
C
F
N
Y
L
L
L
D
P
R
I
T
K
D
Nematode Worm
Caenorhab. elegans
NP_492539
732
81526
K512
F
K
N
Q
I
L
V
K
R
N
S
P
Q
L
E
Sea Urchin
Strong. purpuratus
XP_781548
802
88988
V525
L
D
S
G
E
E
E
V
P
H
R
L
E
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
79.6
54.9
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
21
31.4
Protein Similarity:
100
98.2
81.2
60.7
N.A.
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
41.9
34.2
43
P-Site Identity:
100
100
86.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
33.3
P-Site Similarity:
100
100
86.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
0
0
0
0
0
0
0
0
0
13
0
13
38
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
13
0
0
0
13
0
13
0
0
13
13
% D
% Glu:
0
13
0
0
13
50
13
13
13
13
0
0
50
0
13
% E
% Phe:
13
0
13
0
0
0
38
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
0
0
13
0
38
0
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
25
0
0
0
13
0
0
0
0
0
0
13
0
13
0
% I
% Lys:
0
13
0
0
0
0
0
13
0
0
0
0
0
13
0
% K
% Leu:
13
13
38
0
13
25
13
13
0
0
0
63
0
50
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
13
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
0
13
0
38
25
0
0
13
13
0
13
13
0
13
% P
% Gln:
0
0
0
13
0
0
0
0
0
13
0
0
13
0
0
% Q
% Arg:
25
0
13
0
0
0
13
0
13
0
25
0
0
0
13
% R
% Ser:
0
0
13
0
0
0
0
38
0
0
63
0
13
0
0
% S
% Thr:
13
0
0
0
0
0
0
13
13
0
0
0
13
0
13
% T
% Val:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _