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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKLE1
All Species:
10.61
Human Site:
Y201
Identified Species:
33.33
UniProt:
Q8NAG6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAG6
NP_689576.4
575
62235
Y201
S
P
P
G
H
W
D
Y
S
S
D
A
S
F
V
Chimpanzee
Pan troglodytes
XP_001173375
575
62144
Y201
S
P
P
G
H
W
D
Y
S
S
D
A
S
L
V
Rhesus Macaque
Macaca mulatta
XP_001114324
683
73209
Y283
S
P
P
G
H
W
D
Y
S
S
D
A
S
F
I
Dog
Lupus familis
XP_852664
443
49437
F131
C
A
R
V
L
R
E
F
Q
R
Q
R
R
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519527
622
67527
G192
G
S
P
G
D
D
D
G
D
A
G
S
S
S
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395966
443
50476
L131
A
F
D
E
E
F
N
L
G
K
E
V
A
R
S
Nematode Worm
Caenorhab. elegans
NP_492539
732
81526
P275
T
P
E
A
I
L
N
P
R
K
Q
R
T
P
V
Sea Urchin
Strong. purpuratus
XP_781548
802
88988
S281
S
S
S
A
S
N
R
S
S
S
S
S
S
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
79.6
54.9
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
21
31.4
Protein Similarity:
100
98.2
81.2
60.7
N.A.
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
41.9
34.2
43
P-Site Identity:
100
93.3
93.3
0
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
33.3
P-Site Similarity:
100
93.3
100
13.3
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
0
25
0
0
0
0
0
13
0
38
13
13
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
13
13
50
0
13
0
38
0
0
0
0
% D
% Glu:
0
0
13
13
13
0
13
0
0
0
13
0
0
0
0
% E
% Phe:
0
13
0
0
0
13
0
13
0
0
0
0
0
25
0
% F
% Gly:
13
0
0
50
0
0
0
13
13
0
13
0
0
0
0
% G
% His:
0
0
0
0
38
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
13
0
13
0
0
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
25
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
50
0
0
0
0
13
0
0
0
0
0
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
25
0
0
0
0
% Q
% Arg:
0
0
13
0
0
13
13
0
13
13
0
25
13
13
13
% R
% Ser:
50
25
13
0
13
0
0
13
50
50
13
25
63
13
13
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% T
% Val:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
50
% V
% Trp:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _