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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKLE1
All Species:
15.45
Human Site:
Y532
Identified Species:
48.57
UniProt:
Q8NAG6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAG6
NP_689576.4
575
62235
Y532
N
Q
K
Q
G
H
C
Y
G
V
V
A
G
W
P
Chimpanzee
Pan troglodytes
XP_001173375
575
62144
Y532
N
Q
K
Q
G
H
C
Y
G
V
V
A
G
W
P
Rhesus Macaque
Macaca mulatta
XP_001114324
683
73209
Y640
N
Q
K
Q
G
H
C
Y
G
V
V
A
G
W
P
Dog
Lupus familis
XP_852664
443
49437
P436
E
G
E
R
E
L
R
P
Q
D
I
Q
A
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519527
622
67527
Y579
N
Q
K
K
G
N
Y
Y
G
V
V
A
S
W
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395966
443
50476
R436
I
F
L
Y
E
G
E
R
Q
I
L
P
Q
N
L
Nematode Worm
Caenorhab. elegans
NP_492539
732
81526
H669
N
K
K
A
G
E
F
H
G
T
T
K
S
W
D
Sea Urchin
Strong. purpuratus
XP_781548
802
88988
Y759
N
A
K
R
G
D
Y
Y
G
V
A
H
S
W
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
79.6
54.9
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
21
31.4
Protein Similarity:
100
98.2
81.2
60.7
N.A.
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
41.9
34.2
43
P-Site Identity:
100
100
100
0
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
33.3
46.6
P-Site Similarity:
100
100
100
20
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
13
0
0
0
0
0
0
13
50
13
0
0
% A
% Cys:
0
0
0
0
0
0
38
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
13
0
0
0
0
13
% D
% Glu:
13
0
13
0
25
13
13
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
75
13
0
0
75
0
0
0
38
0
13
% G
% His:
0
0
0
0
0
38
0
13
0
0
0
13
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
13
13
0
0
0
0
% I
% Lys:
0
13
75
13
0
0
0
0
0
0
0
13
0
0
0
% K
% Leu:
0
0
13
0
0
13
0
0
0
0
13
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
50
% P
% Gln:
0
50
0
38
0
0
0
0
25
0
0
13
13
0
0
% Q
% Arg:
0
0
0
25
0
0
13
13
0
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
63
50
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% W
% Tyr:
0
0
0
13
0
0
25
63
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _