KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM73A
All Species:
33.64
Human Site:
S508
Identified Species:
67.27
UniProt:
Q8NAN2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAN2
NP_940951.1
632
71006
S508
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Chimpanzee
Pan troglodytes
XP_524744
640
71906
S516
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001099577
640
71790
S516
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Dog
Lupus familis
XP_537107
667
74974
S543
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q4QQM5
600
67517
S476
K
E
S
A
V
A
S
S
C
W
S
V
L
K
Q
Rat
Rattus norvegicus
NP_001100036
554
61374
E446
M
D
A
F
E
D
L
E
N
P
P
S
S
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506555
853
94104
S729
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Chicken
Gallus gallus
XP_001234741
601
67721
S477
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Frog
Xenopus laevis
Q6NRB7
570
64680
S462
F
K
E
T
A
V
T
S
S
C
W
S
V
L
R
Zebra Danio
Brachydanio rerio
Q5XJS0
595
66907
S471
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572476
525
59005
S417
V
V
Q
N
R
W
L
S
N
G
F
K
E
T
A
Honey Bee
Apis mellifera
XP_394437
412
47282
F304
N
R
W
I
S
A
S
F
R
E
T
A
I
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.8
88
N.A.
80.5
35.7
N.A.
63.7
82.2
62.8
57.9
N.A.
28.7
29.1
N.A.
N.A.
Protein Similarity:
100
98.7
98.2
90.5
N.A.
87.9
52.8
N.A.
67.7
87.8
74.6
73
N.A.
47.1
45.2
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
100
100
6.6
100
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
33.3
100
N.A.
6.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
67
9
75
0
0
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
67
9
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
67
9
0
9
0
0
9
0
9
0
0
9
0
0
% E
% Phe:
9
0
0
9
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
67
9
0
0
0
0
0
0
0
0
0
9
0
67
0
% K
% Leu:
0
0
0
0
0
0
17
0
0
0
0
0
67
9
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
67
% Q
% Arg:
0
9
0
0
9
0
0
0
9
0
0
0
0
0
9
% R
% Ser:
0
0
9
0
9
0
75
84
9
0
67
17
9
0
0
% S
% Thr:
0
0
59
9
0
0
9
0
0
0
9
0
0
9
9
% T
% Val:
9
9
0
0
67
9
0
0
0
0
0
67
9
9
0
% V
% Trp:
0
0
9
0
0
9
0
0
0
67
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _