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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGO61 All Species: 37.88
Human Site: S260 Identified Species: 83.33
UniProt: Q8NAT1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NAT1 NP_116195.2 580 66615 S260 P K A N I L V S G N E I R Q F
Chimpanzee Pan troglodytes Q5NDF1 580 66537 S260 P K A N I L V S G N E I R Q F
Rhesus Macaque Macaca mulatta XP_001108195 470 53514 P174 V F H D D L L P L F Y T L R Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BW41 605 69360 S260 P K A N I L V S G N E I R Q F
Rat Rattus norvegicus Q5NDF0 580 66699 S260 P K A N I L V S G N E I R Q F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508787 590 66593 S262 P K A N I L V S G G E I R Q F
Chicken Gallus gallus Q5NDE8 577 66736 S259 P K A N I L V S G N E I R Q F
Frog Xenopus laevis Q5NDE7 578 66966 S259 P K A N I L V S G N E I R H F
Zebra Danio Brachydanio rerio Q5NDE5 578 67038 S259 P K A N I L I S G N E I R Q F
Tiger Blowfish Takifugu rubipres Q5NDE4 590 68013 S259 P K A N I L V S G N E I R H F
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791565 610 68478 T266 P L D D I A V T S K E I T L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 80.1 N.A. N.A. 88.9 93.4 N.A. 80.5 79.6 75 72.4 69.3 N.A. N.A. N.A. 39.6
Protein Similarity: 100 99.6 80.5 N.A. N.A. 92 96.9 N.A. 87.2 89.6 88 85.1 83.2 N.A. N.A. N.A. 56.2
P-Site Identity: 100 100 6.6 N.A. N.A. 100 100 N.A. 93.3 100 93.3 93.3 93.3 N.A. N.A. N.A. 40
P-Site Similarity: 100 100 26.6 N.A. N.A. 100 100 N.A. 93.3 100 93.3 100 93.3 N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 82 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 19 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 91 % F
% Gly: 0 0 0 0 0 0 0 0 82 10 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 19 0 % H
% Ile: 0 0 0 0 91 0 10 0 0 0 0 91 0 0 0 % I
% Lys: 0 82 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 91 10 0 10 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 82 0 0 0 0 0 73 0 0 0 0 0 % N
% Pro: 91 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 82 10 0 % R
% Ser: 0 0 0 0 0 0 0 82 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 10 10 0 0 % T
% Val: 10 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _