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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGO61
All Species:
34.24
Human Site:
S456
Identified Species:
75.33
UniProt:
Q8NAT1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAT1
NP_116195.2
580
66615
S456
D
T
K
V
D
I
P
S
L
I
Q
T
I
R
R
Chimpanzee
Pan troglodytes
Q5NDF1
580
66537
S456
D
T
K
V
D
I
P
S
L
I
Q
T
I
R
R
Rhesus Macaque
Macaca mulatta
XP_001108195
470
53514
R358
T
T
L
F
L
P
G
R
P
G
P
R
K
Q
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW41
605
69360
S456
D
T
R
V
D
I
P
S
L
M
Q
S
I
R
R
Rat
Rattus norvegicus
Q5NDF0
580
66699
S456
D
T
R
V
D
I
P
S
L
M
Q
S
I
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508787
590
66593
S466
D
T
R
V
D
L
P
S
L
I
Q
A
I
R
G
Chicken
Gallus gallus
Q5NDE8
577
66736
S454
D
T
K
V
D
I
P
S
L
I
H
V
I
R
Q
Frog
Xenopus laevis
Q5NDE7
578
66966
S454
D
T
K
V
N
I
S
S
L
I
Q
V
I
K
S
Zebra Danio
Brachydanio rerio
Q5NDE5
578
67038
S455
D
T
T
V
D
L
A
S
F
L
D
V
L
R
D
Tiger Blowfish
Takifugu rubipres
Q5NDE4
590
68013
S466
D
T
L
V
D
I
P
S
F
L
E
V
L
Q
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791565
610
68478
S463
D
T
I
V
D
V
D
S
F
V
E
V
V
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
80.1
N.A.
N.A.
88.9
93.4
N.A.
80.5
79.6
75
72.4
69.3
N.A.
N.A.
N.A.
39.6
Protein Similarity:
100
99.6
80.5
N.A.
N.A.
92
96.9
N.A.
87.2
89.6
88
85.1
83.2
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
100
6.6
N.A.
N.A.
80
80
N.A.
73.3
80
66.6
40
46.6
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
20
N.A.
N.A.
100
100
N.A.
86.6
86.6
80
60
73.3
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
91
0
0
0
82
0
10
0
0
0
10
0
0
0
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
28
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
64
0
0
0
46
0
0
64
0
0
% I
% Lys:
0
0
37
0
0
0
0
0
0
0
0
0
10
10
10
% K
% Leu:
0
0
19
0
10
19
0
0
64
19
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
64
0
10
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
55
0
0
19
10
% Q
% Arg:
0
0
28
0
0
0
0
10
0
0
0
10
0
73
37
% R
% Ser:
0
0
0
0
0
0
10
91
0
0
0
19
0
0
10
% S
% Thr:
10
100
10
0
0
0
0
0
0
0
0
19
0
0
0
% T
% Val:
0
0
0
91
0
10
0
0
0
10
0
46
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _