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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF38A
All Species:
22.73
Human Site:
S193
Identified Species:
41.67
UniProt:
Q8NAV1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAV1
NP_116253.2
312
37477
S193
E
D
M
D
D
V
E
S
S
E
E
E
E
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111695
312
37444
S193
E
D
M
D
D
V
E
S
S
E
E
E
E
E
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q4FK66
312
37418
S193
E
D
M
D
D
V
E
S
S
E
E
E
E
E
E
Rat
Rattus norvegicus
Q6AXY7
542
63914
D351
D
R
K
G
D
R
R
D
R
D
R
E
R
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234245
312
37442
S193
E
D
M
D
D
V
E
S
S
E
E
E
E
E
E
Frog
Xenopus laevis
Q4FZQ6
312
37276
S193
E
D
M
D
D
V
E
S
S
E
E
E
E
D
D
Zebra Danio
Brachydanio rerio
Q6DHU4
313
37532
T193
E
D
L
D
E
V
E
T
S
E
E
E
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610463
330
40069
P193
E
D
L
D
D
E
L
P
S
D
E
E
K
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23121
312
35023
G192
C
D
G
M
D
L
N
G
R
K
I
K
M
I
D
Sea Urchin
Strong. purpuratus
XP_781290
318
36969
D193
E
D
L
D
D
M
E
D
S
S
D
D
D
I
D
Poplar Tree
Populus trichocarpa
XP_002319497
297
35725
P179
E
T
L
A
A
L
E
P
R
K
S
V
L
E
D
Maize
Zea mays
NP_001151258
389
46781
E193
D
D
F
E
E
E
E
E
D
K
E
E
Q
P
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565937
355
43154
K213
D
E
M
D
Q
R
R
K
S
P
E
R
E
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
N.A.
N.A.
98.7
23.6
N.A.
N.A.
97.7
91.6
88.5
N.A.
53.6
N.A.
20.5
51.2
Protein Similarity:
100
N.A.
99.6
N.A.
N.A.
99
35.6
N.A.
N.A.
99
96.7
96.1
N.A.
67.5
N.A.
33.9
64.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
20
N.A.
N.A.
100
86.6
66.6
N.A.
46.6
N.A.
13.3
40
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
40
N.A.
N.A.
100
100
100
N.A.
73.3
N.A.
40
80
Percent
Protein Identity:
54.1
48.3
N.A.
47.3
N.A.
N.A.
Protein Similarity:
66.9
58.6
N.A.
62.5
N.A.
N.A.
P-Site Identity:
20
26.6
N.A.
40
N.A.
N.A.
P-Site Similarity:
46.6
60
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
77
0
70
70
0
0
16
8
16
8
8
16
16
39
% D
% Glu:
70
8
0
8
16
16
70
8
0
47
70
70
47
47
47
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
24
0
8
8
0
8
% K
% Leu:
0
0
31
0
0
16
8
0
0
0
0
0
8
0
0
% L
% Met:
0
0
47
8
0
8
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
16
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
16
16
0
24
0
8
8
8
8
0
% R
% Ser:
0
0
0
0
0
0
0
39
70
8
8
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
47
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _