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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF38A
All Species:
44.24
Human Site:
T68
Identified Species:
81.11
UniProt:
Q8NAV1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAV1
NP_116253.2
312
37477
T68
Y
G
G
N
I
K
P
T
P
F
L
C
L
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111695
312
37444
T68
Y
G
G
N
I
K
P
T
P
F
L
C
L
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q4FK66
312
37418
T68
Y
G
G
N
I
K
P
T
P
F
L
C
L
T
L
Rat
Rattus norvegicus
Q6AXY7
542
63914
S126
V
G
T
G
G
I
V
S
T
A
F
C
L
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234245
312
37442
T68
Y
G
G
N
I
K
P
T
P
F
L
C
L
T
L
Frog
Xenopus laevis
Q4FZQ6
312
37276
T68
Y
G
G
N
I
K
P
T
P
F
L
C
L
T
L
Zebra Danio
Brachydanio rerio
Q6DHU4
313
37532
T68
Y
G
G
N
V
K
P
T
P
F
L
C
L
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610463
330
40069
T68
Y
G
G
N
I
K
P
T
Q
F
L
C
L
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23121
312
35023
G81
R
G
G
G
G
D
R
G
G
F
G
G
G
G
R
Sea Urchin
Strong. purpuratus
XP_781290
318
36969
S68
Y
G
G
N
I
K
P
S
P
F
L
C
L
L
L
Poplar Tree
Populus trichocarpa
XP_002319497
297
35725
T68
Y
G
G
N
R
K
P
T
P
F
M
C
L
V
M
Maize
Zea mays
NP_001151258
389
46781
T68
Y
G
G
N
R
K
P
T
P
F
L
C
L
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565937
355
43154
T68
F
G
G
S
R
K
P
T
P
F
L
C
L
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
N.A.
N.A.
98.7
23.6
N.A.
N.A.
97.7
91.6
88.5
N.A.
53.6
N.A.
20.5
51.2
Protein Similarity:
100
N.A.
99.6
N.A.
N.A.
99
35.6
N.A.
N.A.
99
96.7
96.1
N.A.
67.5
N.A.
33.9
64.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
20
N.A.
N.A.
100
100
93.3
N.A.
93.3
N.A.
20
86.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
26.6
N.A.
N.A.
100
100
100
N.A.
93.3
N.A.
20
93.3
Percent
Protein Identity:
54.1
48.3
N.A.
47.3
N.A.
N.A.
Protein Similarity:
66.9
58.6
N.A.
62.5
N.A.
N.A.
P-Site Identity:
73.3
86.6
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
93
8
0
0
0
0
% F
% Gly:
0
100
93
16
16
0
0
8
8
0
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
54
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
85
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
77
0
93
16
77
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
85
0
77
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
24
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
77
8
0
0
0
0
54
0
% T
% Val:
8
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _