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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD1
All Species:
22.42
Human Site:
T434
Identified Species:
54.81
UniProt:
Q8NB12
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB12
NP_938015.1
490
56617
T434
H
G
P
S
H
P
I
T
K
D
L
E
A
M
R
Chimpanzee
Pan troglodytes
XP_514316
454
52196
F388
M
E
P
Y
R
I
F
F
P
G
S
H
P
V
R
Rhesus Macaque
Macaca mulatta
XP_001093225
479
54825
T423
H
G
P
S
H
P
I
T
K
D
L
E
A
M
R
Dog
Lupus familis
XP_852104
490
56440
T434
H
G
P
S
H
P
I
T
K
D
L
E
A
M
R
Cat
Felis silvestris
Mouse
Mus musculus
P97443
485
55988
T429
H
G
P
S
H
P
I
T
K
D
L
E
A
M
R
Rat
Rattus norvegicus
Q7M6Z3
433
49630
A382
P
V
Y
S
L
N
V
A
S
M
W
L
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510487
490
56179
T434
H
G
P
T
H
P
I
T
K
D
L
E
A
M
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085463
478
54748
T417
H
G
P
S
H
P
I
T
K
D
L
E
M
M
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
K377
D
P
A
I
L
F
Q
K
Y
Q
L
A
Q
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
Q423
I
G
L
Q
F
Y
T
Q
G
K
L
E
W
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.7
85.5
96.1
N.A.
93.6
28.5
N.A.
87.5
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
46.1
90.1
99.1
N.A.
97.7
49.5
N.A.
95.5
N.A.
84.9
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
93.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
10
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
70
0
0
0
% E
% Phe:
0
0
0
0
10
10
10
10
0
0
0
0
0
0
10
% F
% Gly:
0
70
0
0
0
0
0
0
10
10
0
0
0
0
10
% G
% His:
60
0
0
0
60
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
10
0
10
60
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
60
10
0
0
10
0
0
% K
% Leu:
0
0
10
0
20
0
0
0
0
0
80
10
0
30
10
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
10
60
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
70
0
0
60
0
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
10
0
0
10
10
0
10
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
70
% R
% Ser:
0
0
0
60
0
0
0
0
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
10
60
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
10
10
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _